Evidence map›Paper›PMID 32517867›Full record

ArticleJournal of biomechanics2020

Lower knee extensor and flexor strength is associated with varus thrust in people with knee osteoarthritis.

Sofia E Espinosa, Kerry E Costello, Richard B Souza, Deepak Kumar

Abstract read
In one paragraph

Article in Journal of biomechanics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Assessment of varus thrust using inertial measurement units.Clinical biomechanics (Bristol, Avon) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sofia E EspinosaPhysical Therapy & Athletic Training, Boston University, United States.
Kerry E CostelloPhysical Therapy & Athletic Training, Boston University, United States; Division of Rheumatology, Department of Medicine, Boston University, School of Medicine, United States.
Richard B SouzaPhysical Therapy and Rehabilitation Science, University of California, San Francisco, United States; Department of Radiology and Biomedical Imaging, University of California, San Francisco, United States.
Deepak KumarPhysical Therapy & Athletic Training, Boston University, United States; Division of Rheumatology, Department of Medicine, Boston University, School of Medicine, United States; Department of Radiology and Biomedical Imaging, University of California, San Francisco, United States. Electronic address: kumard@bu.edu.

Funding

MRI TO STUDY CARTILAGE/BONE INTERACTIONSR01AR046905 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MAJUMDAR, SHARMILA · 1999 to 2015
$6.3M
Mentoring Biomechanics Research in OsteoarthritisK24AR072133 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Richard Brian Souza · 2018 to 2026
$1.5M
Contact mechanics, neuromuscular control, and cartilage composition in knee OAR01AR062370 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SOUZA, RICHARD BRIAN · 2011 to 2014
$1.1M
Mind Your Walk Intervention for Community-Based Management of Knee OA: A Feasibility StudyK01AR069720 · NIAMS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI KUMAR, DEEPAK · 2017 to 2021
$676k
NIAMS NIH HHS K01 AR069720NIAMS NIH HHS K24 AR072133NIAMS NIH HHS R01 AR046905NIAMS NIH HHS R01 AR062370
6 · The paper itself

Abstract

Varus thrust during walking is common in people with knee osteoarthritis (OA) and can increase the risk of disease progression. Lower limb muscle strength, particularly isokinetic strength, may play a role in varus thrust. The purpose of this study was to investigate the relationships between varus thrust and isokinetic strength knee extensors and flexors in people with and without knee OA . Data from participants with (n = 28) and without (n = 68) knee OA were used. All participants underwent gait analysis during walking at a self-selected pace. Isokinetic knee extensor and flexor strength were measured at 60°/s and 120°/s. Varus thrust was measured using peak knee adduction velocity and knee adduction excursion during the first half of stance. Multiple linear regression was used to examine relationships between strength and varus thrust in the two groups separately while adjusting for age, sex, walking speed, and static alignment. In those with knee OA, knee extensor (Model R

Indexed as

Osteoarthritis, KneeBiomechanical PhenomenaGaitHumansKneeKnee JointHamstringsKneeOsteoarthritisQuadricepsVarus thrust

Identifiers

PMID32517867
PMCPMC7322620

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.