Evidence map›Paper›PMID 32517741›Full record

ArticleBMC research notes2020

Are patients on oral anticoagulation therapy aware of its effects? A cross-sectional study from Karachi, Pakistan.

Ibrahim Zahid, Syed Wajih Ul Hassan, Nida Sehar Bhurya, Sheena Nadeem Alam, Choudhary Ahmed Hasan, Bakht Hussain Shah, Fasiha Bakhtawar Fatima, Ayesha Ahmed, Syed Sabih Ul Hassan, Javeria Hayat and 6 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in BMC research notes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

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  12. Knowledge, Adherence, and Satisfaction With Warfarin Therapy and Associated Factors Among Outpatients at University Teaching Hospital in Ethiopia.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 2 countries.

Ibrahim ZahidDow Medical College, Dow University of Health Sciences, Karachi, Pakistan. ibrahim_zahid@hotmail.com.ORCID http://orcid.org/0000-0002-0638-379X
Syed Wajih Ul HassanDr. Ruth K.M. Pfau Civil Hospital, Karachi, Pakistan.
Nida Sehar BhuryaDr. Ruth K.M. Pfau Civil Hospital, Karachi, Pakistan.
Sheena Nadeem AlamDr. Ruth K.M. Pfau Civil Hospital, Karachi, Pakistan.
Choudhary Ahmed HasanDow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Bakht Hussain ShahDow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Fasiha Bakhtawar FatimaDow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Ayesha AhmedDr. Ruth K.M. Pfau Civil Hospital, Karachi, Pakistan.
Syed Sabih Ul HassanDow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Javeria HayatDow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Aqsa ZulfiqarDr. Ruth K.M. Pfau Civil Hospital, Karachi, Pakistan.
Rija SheikhDr. Ruth K.M. Pfau Civil Hospital, Karachi, Pakistan.
Momin AzizDow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Rabbia SiddiqiDow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Kaneez FatimaDow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Muhammad Shahzeb KhanJohn H Stroger Jr. Hospital of Cook County, Chicago, IL, USA.
Dow University of Health Sciences · PKCivil Hospital Karachi · PKJohn H. Stroger, Jr. Hospital of Cook County · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveOral anticoagulants are one of the most frequently used medications. However, these drugs have a range of side effects including potential life-threatening complications. Little is known regarding the awareness of its side effect profile amongst the patients in Pakistan. Therefore, the aim of this study was to assess the knowledge of oral anticoagulant therapy and its side effects among its users.

resultsThe mean age was 48.9 ± 15.2 years. Median scores of the participants for knowledge regarding oral anticoagulants and warfarin were 48.7 (8.3-91.7) and 10.3 (0.0-70.0) respectively. Of 207 patients, most notably, 65.7% did not know what side effects to be wary of or how to reduce their occurrence; and most patients were unaware of the interaction between oral anticoagulant drugs and over-the-counter substances such as aspirin, herbal medicines and alcohol. Knowledge of international normalised ratio (INR) was extremely poor with more than 75% of the population not being aware of the target INR range during warfarin therapy. Higher level of education was significantly associated with better knowledge scores. Overall, knowledge of oral anticoagulant therapy and INR monitoring is extremely poor among oral anticoagulant users.

Indexed as

Health Knowledge, Attitudes, PracticeInternational Normalized RatioAdministration, OralAdultAgedAnticoagulantsCross-Sectional StudiesDrug InteractionsFemaleHumansMaleMiddle AgedPakistanWarfarinAnticoagulantsWarfarinAnticoagulantsInternational normalised ratioWarfarin

Identifiers

PMID32517741
PMCPMC7285618
OpenAlexW3034002752

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.