Evidence map›Paper›PMID 32517714›Full record

ArticleBMC nephrology2020

Ethnic minority disparities in progression and mortality of pre-dialysis chronic kidney disease: a systematic scoping review.

Hilda O Hounkpatin, Simon D S Fraser, Rory Honney, Gavin Dreyer, Alison Brettle, Paul J Roderick

Open access · goldAbstract readScoping Review
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it, 87 citations in OpenAlex.

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  5. Water intake mediates cross-sectional associations between urinary kidney injury biomarkers and race in emerging adults.American journal of physiology. Regulatory, integrative and comparative physiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Hilda O HounkpatinSchool of Primary Care, Population Sciences and Medical Education, Faculty of Medicine, South Academic Block, University of Southampton, Southampton General Hospital, Tremona Road, Room AC18 Level C, Southampton, SO16 6YD, UK. H.O.Hounkpatin@soton.ac.uk.
Simon D S FraserSchool of Primary Care, Population Sciences and Medical Education, Faculty of Medicine, South Academic Block, University of Southampton, Southampton General Hospital, Tremona Road, Room AC18 Level C, Southampton, SO16 6YD, UK.
Rory HonneySchool of Primary Care, Population Sciences and Medical Education, Faculty of Medicine, South Academic Block, University of Southampton, Southampton General Hospital, Tremona Road, Room AC18 Level C, Southampton, SO16 6YD, UK.
Gavin DreyerDepartment of Nephrology, Barts Health NHS Trust, London, UK.
Alison BrettleSchool of Nursing, Midwifery, Social Work and Social Sciences, University of Salford, Rm 1.47, Mary Seacole Building, Frederick Road, Salford, M6 6PU, UK.
Paul J RoderickSchool of Primary Care, Population Sciences and Medical Education, Faculty of Medicine, South Academic Block, University of Southampton, Southampton General Hospital, Tremona Road, Room AC18 Level C, Southampton, SO16 6YD, UK.
University of Southampton · GBBarts Health NHS Trust · GBSouthampton General Hospital · GBUniversity of Salford · GB

Funding

Kidney Research UK N/A
6 · The paper itself

Abstract

backgroundThere are a growing number of studies on ethnic differences in progression and mortality for pre-dialysis chronic kidney disease (CKD), but this literature has yet to be synthesised, particularly for studies on mortality.

methodsThis scoping review synthesized existing literature on ethnic differences in progression and mortality for adults with pre-dialysis CKD, explored factors contributing to these differences, and identified gaps in the literature. A comprehensive search strategy using search terms for ethnicity and CKD was taken to identify potentially relevant studies. Nine databases were searched from 1992 to June 2017, with an updated search in February 2020.

results8059 articles were identified and screened. Fifty-five studies (2 systematic review, 7 non-systematic reviews, and 46 individual studies) were included in this review. Most were US studies and compared African-American/Afro-Caribbean and Caucasian populations, and fewer studies assessed outcomes for Hispanics and Asians. Most studies reported higher risk of CKD progression in Afro-Caribbean/African-Americans, Hispanics, and Asians, lower risk of mortality for Asians, and mixed findings on risk of mortality for Afro-Caribbean/African-Americans and Hispanics, compared to Caucasians. Biological factors such as hypertension, diabetes, and cardiovascular disease contributed to increased risk of progression for ethnic minorities but did not increase risk of mortality in these groups.

conclusionsHigher rates of renal replacement therapy among ethnic minorities may be partly due to increased risk of progression and reduced mortality in these groups. The review identifies gaps in the literature and highlights a need for a more structured approach by researchers that would allow higher confidence in single studies and better harmonization of data across studies to advance our understanding of CKD progression and mortality.

Indexed as

Disease ProgressionEthnicityHumansMinority GroupsRenal DialysisRenal Insufficiency, ChronicChronic kidney diseaseEnd stage renal diseaseEpidemiologyEthnicityPre-dialysis

Identifiers

PMID32517714
PMCPMC7282112
OpenAlexW3033196427

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.