Evidence map›Paper›PMID 32517695›Full record

ArticleBMC nephrology2020

Hospitalization and mortality following non-attendance for hemodialysis according to dialysis day of the week: a European cohort study.

James Fotheringham, Michael T Smith, Marc Froissart, Florian Kronenberg, Peter Stenvinkel, Jürgen Floege, Kai-Uwe Eckardt, David C Wheeler

Open access · goldAbstract read
In one paragraph

Article in BMC nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Hemodialysis Nonattendance: Patient Characteristics and Outcomes in a Single Renal Center in North West England.Hemodialysis international. International Symposium on Home Hemodialysis · 2025
    Article
  8. Risk of Major Adverse Cardiovascular Events in Home Dialysis Compared With In-Center Hemodialysis.Clinical journal of the American Society of Nephrology : CJASN · 2025
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 8 institutions in 5 countries.

James FotheringhamNorthern General Hospital, Sheffield Kidney Institute, Herries Road, Sheffield, South Yorkshire, S5 7AU, UK. j.fotheringham@sheffield.ac.uk.
Michael T SmithComputer Science, University of Sheffield, Sheffield, UK.
Marc FroissartClinical Trial Unit, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
Florian KronenbergDivision of Genetic Epidemiology, Medical University of Innsbruck, Innsbruck, Austria.
Peter StenvinkelDepartment of Renal Medicine, Karolinska University Hospital Huddinge, Stockholm, Sweden.
Jürgen FloegeDepartment of Nephrology, RWTH University of Aachen, Aachen, Germany.
Kai-Uwe EckardtDepartment of Nephrology and Medical Intensive Care, Charité - Universitätsmedizin-Berlin, Berlin, Germany.
David C WheelerDepartment of Renal Medicine, University College London, London, UK.
Charité - Universitätsmedizin Berlin · DEKarolinska University Hospital · SERWTH Aachen University · DESheffield Kidney Institute · GBUniversität Innsbruck · ATUniversity College London · GBUniversity Hospital of Lausanne · CHUniversity of Sheffield · GB

Funding

EPA EP-C-15-008National Institute of Health Research (UK) CS-2015-15-008
6 · The paper itself

Abstract

backgroundThe extension of the interdialytic interval due to due to dialysis session non-attendance varies according to which session of the week the patient misses. The impact of this on subsequent hospitalization and mortality is unknown.

methodsThe ARO cohort study prospectively collected data from hemodialysis patients across 15 European countries on demography, comorbidity, laboratory, hospitalisation, mortality and individual hemodialysis sessions from 2007 to 2014. Event rates for death and hospitalisation according to dialysis day of the week were calculated for patients who attended the three previous scheduled hemodialysis sessions, who then on the next scheduled dialysis day either attended or did not attend. The hazard ratio for these events following non-attendance for the first compared to the second dialysis session of the week was estimated using Cox proportional hazards model adjusted for patient demographics.

results3.8 million hemodialysis sessions in 9397 patients were analysed. The non-attendance rates for Monday/Wednesday/Friday sessions were 0.8, 0.9% & 1.4% respectively, and for Tuesday/Thursday/Saturday sessions were 0.6, 1.0% & 1.2% respectively. Compared to those who attended, for the 48-72 h between non-attendance and the next scheduled haemodialysis session, mortality significantly increased from 4.86 to 51.9/100 pt-yrs and hospitalisation increased from 0.58 to 2.1/yr. As time from the two-day break increased, the risk associated with non-attendance lessened: compared to missing the second hemodialysis session, missing the first session had a hazard ratio for mortality of 2.04 (95% CI 1.27-3.29), and for hospitalisation 1.78 (95% CI 1.29-2.47). In patients who attended their scheduled dialysis session and the three preceding, after the two-day break there were absolute increases in mortality (8.3 vs. 4.9/100 pt-yrs) and hospitalisation (1.0 vs. 0.6/yr for the rest of the week) comparable to previous studies.

conclusionsIn addition to hospitalisation and mortality increases seen after the two-day break, additional harm may be manifested in the greater increases in mortality and hospitalisation observed after non-attendance for the first hemodialysis session after the two-day break compared to missing other sessions.

Indexed as

Renal DialysisCohort StudiesEuropeFemaleHospitalizationHumansMaleNo-Show PatientsProportional Hazards ModelsRenal InsufficiencyTime FactorsAdherenceComplianceHemodialysisHospitalisationInterdialytic intervalMortality

Identifiers

PMID32517695
PMCPMC7285433
OpenAlexW3033364403

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.