Evidence map›Paper›PMID 32517330›Full record

ArticleNutrients2020

Lactobacilli Supplemented with Larch Arabinogalactan and Colostrum Stimulates an Immune Response towards Peripheral NK Activation and Gut Tolerance.

Tsvetelina Velikova, Kalina Tumangelova-Yuzeir, Ralitsa Georgieva, Ekaterina Ivanova-Todorova, Elena Karaivanova, Ventsislav Nakov, Radislav Nakov, Dobroslav Kyurkchiev

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Tsvetelina VelikovaClinical Immunology, University Hospital "Lozenetz," Kozyak 1 Str., 1407 Sofia, Medical Faculty, Sofia University St. Kliment Ohridski, 1504 Sofia, Bulgaria.ORCID 0000-0002-0593-1272
Kalina Tumangelova-YuzeirLaboratory of Clinical Immunology, University Hospital "St. Ivan Rilski", Medical University of Sofia, 15 "Acad. Iv. Evst. Geshov" Blvd, 1431 Sofia, Bulgaria.
Ralitsa GeorgievaLactina Ltd., 101 Sofia str., 1720 Bankya, Bulgaria.
Ekaterina Ivanova-TodorovaLaboratory of Clinical Immunology, University Hospital "St. Ivan Rilski", Medical University of Sofia, 15 "Acad. Iv. Evst. Geshov" Blvd, 1431 Sofia, Bulgaria.ORCID 0000-0002-1833-838X
Elena KaraivanovaLactina Ltd., 101 Sofia str., 1720 Bankya, Bulgaria.
Ventsislav NakovClinic of Gastroenterology, University Hospital "Tsaritsa Ioanna-ISUL," 8 Byalo more Str., 1527 Sofia, Bulgaria.
Radislav NakovClinic of Gastroenterology, University Hospital "Tsaritsa Ioanna-ISUL," 8 Byalo more Str., 1527 Sofia, Bulgaria.ORCID 0000-0002-5056-8417
Dobroslav KyurkchievLaboratory of Clinical Immunology, University Hospital "St. Ivan Rilski", Medical University of Sofia, 15 "Acad. Iv. Evst. Geshov" Blvd, 1431 Sofia, Bulgaria.
Medical University of Sofia · BGQueen Giovanna Hospital · BGLozenetz Hospital · BG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Probiotics possibly affect local and systemic immune reactions and maintain the intestinal immune homeostasis in healthy individuals and patients with diseases such as irritable bowel syndrome (IBS). In this single-center, blinded trial, we enrolled 40 individuals (20 patients with IBS and 20 healthy individuals) whose blood and fecal samples were collected before and after a 21-day administration of a product comprising

Indexed as

Dietary SupplementsImmune ToleranceLactobacillusAdultColostrumCytokinesFemaleGalactansHealthy VolunteersHomeostasisHumansImmunoglobulin A, SecretoryIntestinal MucosaIrritable Bowel SyndromeKiller Cells, NaturalLarixarabinogalactanCytokinesGalactansImmunoglobulin A, SecretorycolostrumLactobacillus spp.larch arabinogalactanmucosal cytokinesNK cellsprebioticprobiotic

Identifiers

PMID32517330
PMCPMC7352398
OpenAlexW3033394846

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.