Evidence map›Paper›PMID 32517306›Full record

ArticleNutrients2020

The High-Fat Diet Based on Extra-Virgin Olive Oil Causes Dysbiosis Linked to Colorectal Cancer Prevention.

Carmen Rodríguez-García, Cristina Sánchez-Quesada, Ignacio Algarra, José J Gaforio

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Carmen Rodríguez-GarcíaDepartment of Health Sciences, Faculty of Experimental Sciences, University of Jaén, 23071 Jaén, Spain.ORCID 0000-0002-4531-3188
Cristina Sánchez-QuesadaDepartment of Health Sciences, Faculty of Experimental Sciences, University of Jaén, 23071 Jaén, Spain.ORCID 0000-0003-2997-8515
Ignacio AlgarraDepartment of Health Sciences, Faculty of Experimental Sciences, University of Jaén, 23071 Jaén, Spain.
José J GaforioDepartment of Health Sciences, Faculty of Experimental Sciences, University of Jaén, 23071 Jaén, Spain.ORCID 0000-0003-2996-9301
Universidad de Jaén · ES

Funding

"Centro para el Desarrollo Tecnológico Industrial" (CDTI) and FEDER funds through the "Programa CIEN" (convocatoria 2015) and led by the Company Aceites del Sur-Coosur, S.A. METASIN Project (IDI-20150577)Instituto de Estudios Giennenses 2018.160.3340.45100pre-doctoral research grant from the University of Jaén (Ayudas predoctorales para la formación del personal investigador Acción 4_El_CTS_1_2017)
6 · The paper itself

Abstract

The present study aims to examine the effects of three different high-fat diet (HFD) on mice gut microbiota in order to analyse whether they create the microenvironmental conditions that either promote or prevent colorectal cancer (CRC). We evaluated colonic mucosa-associated microbiota in CD1 mice fed with HFD, based on 60% kcal from fat-containing coconut, sunflower or extra-virgin olive oil as the only source of fat. The main findings were as follows: (a) All HFD produced a decrease in the richness and diversity of the intestinal microbiota that was independent of mouse weight, (b) HFD switched

Indexed as

Diet, High-FatGastrointestinal MicrobiomeOlive OilAkkermansiaAnimalsBacillotaBacteroidetesCoconut OilColorectal NeoplasmsDysbiosisEnterococcusIntestinal MucosaMiceRiskStaphylococcusSunflower OilCoconut OilOlive OilSunflower OilAkkermansiabacteroidetescoconut oilfirmicutesgut microbiomeinflammationNeisseriaPrevotellaStaphylococcussunflower oil

Identifiers

PMID32517306
PMCPMC7352482
OpenAlexW3033568175

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.