Evidence map›Paper›PMID 32517269›Full record

ReviewLife (Basel, Switzerland)2020

State-of-the-Art: Inflammatory and Metabolic Markers in Mood Disorders.

Federico Mucci, Donatella Marazziti, Alessandra Della Vecchia, Stefano Baroni, Paolo Morana, Barbara Carpita, Paola Mangiapane, Florinda Morana, Benedetto Morana, Liliana Dell'Osso

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Secondary Mania induced by TNF-α inhibitors: A systematic review.Psychiatry and clinical neurosciences · 2022
    Pooled it
  2. Article
  3. Article
  4. Review
  5. Obesity and Depression: A Pathophysiotoxic Relationship.International journal of molecular sciences · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Federico MucciDipartimento di Medicina Clinica e Sperimentale, Section of Psychiatry, University of Pisa, 56100 Pisa, Italy.ORCID 0000-0002-9746-8237
Donatella MarazzitiDipartimento di Medicina Clinica e Sperimentale, Section of Psychiatry, University of Pisa, 56100 Pisa, Italy.
Alessandra Della VecchiaDipartimento di Medicina Clinica e Sperimentale, Section of Psychiatry, University of Pisa, 56100 Pisa, Italy.ORCID 0000-0002-7905-9755
Stefano BaroniDipartimento di Medicina Clinica e Sperimentale, Section of Psychiatry, University of Pisa, 56100 Pisa, Italy.
Paolo MoranaCasa di Cura Morana, 91025 Marsala, Italy.
Barbara CarpitaDipartimento di Biotecnologie, Chimica e Farmacia, University of Siena, 53100 Siena, Italy.
Paola MangiapaneCasa di Cura Morana, 91025 Marsala, Italy.
Florinda MoranaCasa di Cura Morana, 91025 Marsala, Italy.
Benedetto MoranaCasa di Cura Morana, 91025 Marsala, Italy.
Liliana Dell'OssoDipartimento di Medicina Clinica e Sperimentale, Section of Psychiatry, University of Pisa, 56100 Pisa, Italy.
University of Pisa · ITUniversity of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mounting evidence highlights the involvement of inflammatory/immune systems and their relationships with neurotransmitters and different metabolic processes in mood disorders. Nevertheless, there is a general agreement that available findings are still inconclusive. Therefore, further investigations are required, aimed at deepening the role of possible alterations of biomarkers in the pathophysiology of mood disorders that might lead to more focused and tailored treatments. The present study is a comprehensive review on these topics that seem to represent intriguing avenues for the development of real innovative therapeutic strategies of mood disorders.

Indexed as

hypothalamus-pituitary-adrenal axisimmune systemmood disordersneuro-inflammationneurotransmitters/neuroreceptorsneurotrophinsoxidative stressserotoninuric acid

Identifiers

PMID32517269
PMCPMC7345093
OpenAlexW3033418805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.