Evidence map›Paper›PMID 32517219›Full record

ArticlePolymers2020

Synthesis and Comparative Study of Nanoparticles Derived from Bovine and Human Serum Albumins.

Yerkeblan Tazhbayev, Olzhas Mukashev, Meiram Burkeyev, Vladimir I Lozinsky

Abstract read
In one paragraph

Article in Polymers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yerkeblan TazhbayevChemical Materials Science and Nanochemistry Laboratory, Buketov Karaganda State University, Karaganda 100028, Kazakhstan.ORCID 0000-0003-4828-2521
Olzhas MukashevChemical Materials Science and Nanochemistry Laboratory, Buketov Karaganda State University, Karaganda 100028, Kazakhstan.ORCID 0000-0002-8040-6515
Meiram BurkeyevChemical Materials Science and Nanochemistry Laboratory, Buketov Karaganda State University, Karaganda 100028, Kazakhstan.
Vladimir I LozinskyA.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Moscow 119991, Russia.

Funding

MES RK (Ministry of Education and Science of the Republic of Kazakhstan) АР05132358
6 · The paper itself

Abstract

This study describes the preparation of nanoparticles derived from bovine serum albumin (BSA) in comparison with the formation of nanoparticles composed of human serum albumin (HSA), when the same preparation procedure was used in both cases. To obtain protein nanoparticles, the method of desolvation with ethanol was employed, followed by the stabilization with urea and cysteine. It was shown that, upon transition from HSA to BSA, the particles with smaller sizes and with a narrower polydispersity were formed. The possibility of the immobilization of the antitumor drug hydroxyurea in such protein nanoparticles by adsorption and inclusion methods has been shown. The drug release profile from the polymer matrix was established.

Indexed as

antitumor agentsbiopolymeric nanoparticlesbovine albumindrug carriers

Identifiers

PMID32517219
PMCPMC7361980

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.