Evidence map›Paper›PMID 32517103›Full record

ArticleInternational journal of molecular sciences2020

Cross-Reactivity of Palladium in a Murine Model of Metal-Induced Allergic Contact Dermatitis.

Hiroaki Shigematsu, Kenichi Kumagai, Motoaki Suzuki, Takanori Eguchi, Ryota Matsubara, Yasunari Nakasone, Keisuke Nasu, Takamasa Yoshizawa, Haruno Ichikawa, Takahiro Mori and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Immunological Mechanisms of Metal Allergies and the Nickel-Specific TCR-pMHC Interface.International journal of environmental research and public health · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Hiroaki ShigematsuDepartment of Oral and Maxillofacial Surgery, Toshiba Rinkan Hospital, 7-9-1 Kamitsuruma, Minami-ku, Sagamihara, Kanagawa 252-0385, Japan.
Kenichi KumagaiDepartment of Oral and Maxillofacial Surgery, School of Dental Medicine, Tsurumi University, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama, Kanagawa 230-8501, Japan.
Motoaki SuzukiDepartment of Clinical Immunology, Clinical Research Center for Rheumatology and Allergy, Sagamihara National Hospital, National Hospital Organization, 18-1 Sakuradai, Minami-ku, Sagamihara, Kanagawa 252-0392, Japan.
Takanori EguchiDepartment of Oral and Maxillofacial Surgery, School of Dental Medicine, Tsurumi University, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama, Kanagawa 230-8501, Japan.
Ryota MatsubaraDepartment of Oral and Maxillofacial Surgery, Saku General Hospital, 197, Usuda, Saku, Nagano 394-0301, Japan.
Yasunari NakasoneDepartment of Oral and Maxillofacial Surgery, Nagano Matsushiro General Hospital, 183, Matsushiro, Nagano 381-1231 Japan.
Keisuke NasuDepartment of Oral and Maxillofacial Surgery, School of Dental Medicine, Tsurumi University, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama, Kanagawa 230-8501, Japan.
Takamasa YoshizawaDepartment of Oral and Maxillofacial Surgery, School of Dental Medicine, Tsurumi University, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama, Kanagawa 230-8501, Japan.
Haruno IchikawaDepartment of Oral and Maxillofacial Surgery, School of Dental Medicine, Tsurumi University, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama, Kanagawa 230-8501, Japan.
Takahiro MoriDepartments of Clinical Oncology and Gastroenterological Surgery, National Hospital Organization Sagamihara National Hospital, National Hospital Organization, 18-1 Sakuradai, Minami-ku, Sagamihara, Kanagawa 252-0392, Japan.
Yoshiki HamadaDepartment of Oral and Maxillofacial Surgery, School of Dental Medicine, Tsurumi University, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama, Kanagawa 230-8501, Japan.
Ryuji SuzukiDepartment of Clinical Immunology, Clinical Research Center for Rheumatology and Allergy, Sagamihara National Hospital, National Hospital Organization, 18-1 Sakuradai, Minami-ku, Sagamihara, Kanagawa 252-0392, Japan.
Tsurumi University · JPNational Sagamihara Hospital · JPNagano Matsushiro General Hospital · JPSaku Central Hospital · JPUniversity of Tsukuba · JP

Funding

Japan Society for the Promotion of Science KAKENHI Grant-in-Aid for Young Scientists B 16K20443, and Grant-in-Aid for Scientific Research C 19K10371.
6 · The paper itself

Abstract

Metal allergy is usually diagnosed by patch testing, however, the results do not necessarily reflect the clinical symptoms because of cross-reactivity between different metals. In this study, we established the novel mouse model of cross-reactive metal allergy, and aimed to elucidate the immune response in terms of T-cell receptor repertoire. This model was classified into two groups: the sensitization to nickel and challenge with palladium group, and the sensitization to chromium and challenge with palladium group. This model developed spongiotic edema with intra- and peri-epithelial infiltration of CD4

Indexed as

AllergensAnimalsCross ReactionsDermatitis, Allergic ContactDisease Models, AnimalDisease SusceptibilityImmunohistochemistryMetals, HeavyMicePalladiumReceptors, Antigen, T-CellT-LymphocytesAllergensMetals, HeavyPalladiumReceptors, Antigen, T-Cellchromiumcontact dermatitiscross-reactivitymetal allergymetal-specific T cellsnickelpalladiumT-cell receptor

Identifiers

PMID32517103
PMCPMC7313072
OpenAlexW3033610561

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.