Evidence map›Paper›PMID 32517085›Full record

ReviewMaterials (Basel, Switzerland)2020

Magnetic Nanomaterials as Contrast Agents for MRI.

Sofia Caspani, Ricardo Magalhães, João Pedro Araújo, Célia Tavares Sousa

Abstract readReview
In one paragraph

Review in Materials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed.

  1. Review
  2. Review
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  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Lanthanide Nanotheranostics in Radiotherapy.International journal of molecular sciences · 2025
    Review
  11. Review
  12. Aqueous-stable Mn(II)-MOF nanoparticles with highJournal of materials chemistry. B · 2025
    Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Tailored Magnetic FeDiagnostics (Basel, Switzerland) · 2025
    Article
  18. Article
  19. Article
  20. Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sofia CaspaniIFIMUP and Departamento de Física e Astronomia, Faculdade de Ciências Universidade do Porto, Rua do Campo Alegre 687, 4169-007 Porto, Portugal.ORCID 0000-0002-1996-768X
Ricardo MagalhãesIFIMUP and Departamento de Física e Astronomia, Faculdade de Ciências Universidade do Porto, Rua do Campo Alegre 687, 4169-007 Porto, Portugal.
João Pedro AraújoIFIMUP and Departamento de Física e Astronomia, Faculdade de Ciências Universidade do Porto, Rua do Campo Alegre 687, 4169-007 Porto, Portugal.ORCID 0000-0002-1646-7727
Célia Tavares SousaIFIMUP and Departamento de Física e Astronomia, Faculdade de Ciências Universidade do Porto, Rua do Campo Alegre 687, 4169-007 Porto, Portugal.ORCID 0000-0003-2879-0051

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnetic Resonance Imaging (MRI) is a powerful, noninvasive and nondestructive technique, capable of providing three-dimensional (3D) images of living organisms. The use of magnetic contrast agents has allowed clinical researchers and analysts to significantly increase the sensitivity and specificity of MRI, since these agents change the intrinsic properties of the tissues within a living organism, increasing the information present in the images. Advances in nanotechnology and materials science, as well as the research of new magnetic effects, have been the driving forces that are propelling forward the use of magnetic nanostructures as promising alternatives to commercial contrast agents used in MRI. This review discusses the principles associated with the use of contrast agents in MRI, as well as the most recent reports focused on nanostructured contrast agents. The potential applications of gadolinium- (Gd) and manganese- (Mn) based nanomaterials and iron oxide nanoparticles in this imaging technique are discussed as well, from their magnetic behavior to the commonly used materials and nanoarchitectures. Additionally, recent efforts to develop new types of contrast agents based on synthetic antiferromagnetic and high aspect ratio nanostructures are also addressed. Furthermore, the application of these materials in theragnosis, either as contrast agents and controlled drug release systems, contrast agents and thermal therapy materials or contrast agents and radiosensitizers, is also presented.

Indexed as

contrast agentsGd-based contrast agentsiron oxide nanoparticlesmagnetic nanodiscsMn-based contrast agentsMRInanomaterialsnanowiressynthetic antiferromagnetic nanostructurestheragnosis

Identifiers

PMID32517085
PMCPMC7321635

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.