Evidence map›Paper›PMID 32517083›Full record

ReviewBiomolecules2020

A Day in the Life of the Exon Junction Complex.

Lena P Schlautmann, Niels H Gehring

Abstract readReview
In one paragraph

Review in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Nonsense-mediated mRNA decay: friend or foe in cancer biology?Cell communication and signaling : CCS · 2026
    Review
  5. Microbiology (Reading, England) · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Gene regulation through exon junction complex modularity.Nature structural & molecular biology · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. AProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lena P SchlautmannInstitute for Genetics, University of Cologne, Zuelpicher Str. 47a, 50674 Cologne, Germany.
Niels H GehringInstitute for Genetics, University of Cologne, Zuelpicher Str. 47a, 50674 Cologne, Germany.ORCID 0000-0001-7792-1164

Funding

Deutsche Forschungsgemeinschaft GE 2014/5-1Deutsche Forschungsgemeinschaft GE 2014/6-1Deutsche Forschungsgemeinschaft GE 2014/6-2Deutsche Forschungsgemeinschaft GE 2014/7-1
6 · The paper itself

Abstract

The exon junction complex (EJC) is an abundant messenger ribonucleoprotein (mRNP) component that is assembled during splicing and binds to mRNAs upstream of exon-exon junctions. EJCs accompany the mRNA during its entire life in the nucleus and the cytoplasm and communicate the information about the splicing process and the position of introns. Specifically, the EJC's core components and its associated proteins regulate different steps of gene expression, including pre-mRNA splicing, mRNA export, translation, and nonsense-mediated mRNA decay (NMD). This review summarizes the most important functions and main protagonists in the life of the EJC. It also provides an overview of the latest findings on the assembly, composition and molecular activities of the EJC and presents them in the chronological order, in which they play a role in the EJC's life cycle.

Indexed as

ExonsRNA SplicingHumansRibonucleoproteinsRNA, Messengermessenger ribonucleoproteinRibonucleoproteinsRNA, Messengergene regulationmRNARNA-binding proteinRNA processing

Identifiers

PMID32517083
PMCPMC7355637

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.