Evidence map›Paper›PMID 32517032›Full record

ArticleVaccines2020

Modified Alphavirus-Vesiculovirus Hybrid Vaccine Vectors for Homologous Prime-Boost Immunotherapy of Chronic Hepatitis B.

Carolina Chiale, Timur O Yarovinsky, Stephen W Mason, Bhaskara R Madina, Manisha Menon, Marie M Krady, Safiehkhatoon Moshkani, Anasuya Chattopadhyay Pal, Bijan Almassian, John K Rose and 2 more

Abstract read
In one paragraph

Article in Vaccines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Therapeutic vaccination for treatment of chronic hepatitis B.Clinical and experimental immunology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Carolina ChialeDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, NY 12208, USA.
Timur O YarovinskyDepartment of Pathology, Yale University School of Medicine, New Haven, CT 06510, USA.
Stephen W MasonCaroGen Corporation, Farmington, CT 06032, USA.
Bhaskara R MadinaCaroGen Corporation, Farmington, CT 06032, USA.
Manisha MenonCaroGen Corporation, Farmington, CT 06032, USA.
Marie M KradyCaroGen Corporation, Farmington, CT 06032, USA.
Safiehkhatoon MoshkaniDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, NY 12208, USA.
Anasuya Chattopadhyay PalDepartment of Pathology, Yale University School of Medicine, New Haven, CT 06510, USA.
Bijan AlmassianCaroGen Corporation, Farmington, CT 06032, USA.
John K RoseDepartment of Pathology, Yale University School of Medicine, New Haven, CT 06510, USA.
Michael D RobekDepartment of Immunology and Microbial Disease, Albany Medical College, Albany, NY 12208, USA.
Valerian NakaarCaroGen Corporation, Farmington, CT 06032, USA.

Funding

GMP MANUFACTURE OF CLINICAL GRADE THERAPEUTIC VACCINE FOR THE TREATMENT OF PATIENTS WITH CHRONIC HBVR44DK113858 · NIDDK · CAROGEN CORPORATION · PI NAKAAR, VALERIAN · 2019 to 2023
$4.4M
Highly Attenuated Vesiculovirus-based Vectors as HBV Therapeutic VaccinesR01AI124006 · NIAID · ALBANY MEDICAL COLLEGE · PI ROBEK, MICHAEL · 2016 to 2020
$2.0M
Enhancing Immunogenicity of VLV-Based Vaccines for Treatment of Chronic HBVR43DK113858 · NIDDK · CAROGEN CORPORATION · PI NAKAAR, VALERIAN · 2018 to 2018
$225k
Connecticut Bioscience Innovation Fund N/AConnecticut Innovations N/ADivision of Intramural Research, National Institute of Allergy and Infectious Diseases R01AI124006NIAID NIH HHS R01 AI124006NIDDK NIH HHS R43DK113858NIDDK NIH HHS R44DK113858
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID32517032
PMCPMC7349932

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.