ReviewSensors (Basel, Switzerland)2020
Muscle Synergies in Parkinson's Disease.
Review in Sensors (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A methodological scoping review on EMG processing and synergy-based results in muscle synergy studies in Parkinson's disease.Frontiers in bioengineering and biotechnology · 2024Pooled it
- Levodopa-induced alterations in vertical center of mass and muscle synergy structure during Parkinsonian gait.Experimental brain research · 2026Article
- The Cortical Contributions to Turning Performance Through Muscle Synergies in Parkinson's Disease: A Mediation Study.Bioengineering (Basel, Switzerland) · 2026Article
- Cross-Modal Synergy Representation of EMG and Joint Angular Acceleration During Gait in Parkinson's Disease Using NMF and Multimodal Matrix Factorization.Sensors (Basel, Switzerland) · 2026Article
- Evolution of Rate of Force Development (RFD) in the Isometric Deadlift Exercise Among Primary and Secondary Education Students.Sports (Basel, Switzerland) · 2026Article
- Automatic Identification of Lower-Limb Neuromuscular Activation Patterns During Gait Using a Textile Wearable Multisensor System.Sensors (Basel, Switzerland) · 2026Article
- Impairment in the behavioral control of body sway, gaze shift, and mental workload in Parkinson's disease.Scientific reports · 2025Article
- Synergy Analysis Between the Temporal Dominance of Sensations and Temporal Liking Curves of Strawberries.Foods (Basel, Switzerland) · 2025Article
- Frequency-specific intermuscular coherence of synergistic muscles during an isometric force generation task.Frontiers in neural circuits · 2025Article
- Amplitude of Lower Limb Muscle Activation in Different Phases of the Illinois Test in Parkinson's Disease Patients: A Pilot Study.Journal of clinical medicine · 2024Article
- Kinematic network of joint motion provides insight on gait coordination: An observational study on Parkinson's disease.Heliyon · 2024Article
- Muscle Synergy Analysis as a Tool for Assessing the Effectiveness of Gait Rehabilitation Therapies: A Methodological Review and Perspective.Bioengineering (Basel, Switzerland) · 2024Review
- Transferring Sensor-Based Assessments to Clinical Practice: The Case of Muscle Synergies.Sensors (Basel, Switzerland) · 2024Article
- Rectified Latent Variable Model-Based EMG Factorization of Inhibitory Muscle Synergy Components Related to Aging, Expertise and Force-Tempo Variations.Sensors (Basel, Switzerland) · 2024Article
- Article
- Muscle synergies for evaluating upper limb in clinical applications: A systematic review.Heliyon · 2023Review
- Muscle synergies in Parkinson's disease before and after the deep brain stimulation of the bilateral subthalamic nucleus.Scientific reports · 2023Article
- The Measure of Motion Similarity for Robotics Application.Sensors (Basel, Switzerland) · 2023Article
- Usability of the REHOME Solution for the Telerehabilitation in Neurological Diseases: Preliminary Results on Motor and Cognitive Platforms.Sensors (Basel, Switzerland) · 2022Article
- Clarify Sit-to-Stand Muscle Synergy and Tension Changes in Subacute Stroke Rehabilitation by Musculoskeletal Modeling.Frontiers in systems neuroscience · 2022Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over the last two decades, experimental studies in humans and other vertebrates have increasingly used muscle synergy analysis as a computational tool to examine the physiological basis of motor control. The theoretical background of muscle synergies is based on the potential ability of the motor system to coordinate muscles groups as a single unit, thus reducing high-dimensional data to low-dimensional elements. Muscle synergy analysis may represent a new framework to examine the pathophysiological basis of specific motor symptoms in Parkinson's disease (PD), including balance and gait disorders that are often unresponsive to treatment. The precise mechanisms contributing to these motor symptoms in PD remain largely unknown. A better understanding of the pathophysiology of balance and gait disorders in PD is necessary to develop new therapeutic strategies. This narrative review discusses muscle synergies in the evaluation of motor symptoms in PD. We first discuss the theoretical background and computational methods for muscle synergy extraction from physiological data. We then critically examine studies assessing muscle synergies in PD during different motor tasks including balance, gait and upper limb movements. Finally, we speculate about the prospects and challenges of muscle synergy analysis in order to promote future research protocols in PD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.