ArticleJournal of clinical medicine2020
May VelScope Be Deemed an Opportunistic Oral Cancer Screening by General Dentists? A Pilot Study.
Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Current knowledge, attitude and practice among dental hygienists in oral cancer awareness: Systematic review.International journal of dental hygiene · 2022Pooled it
- Beyond Visual Inspection: A Systematic Review of Adjunctive Aids for the Early Detection of Oral Squamous Cell Carcinoma.Journal of clinical medicine · 2026Review
- Evaluating the Role of VELscope in Oral Cancer and Pre-Cancer Screening: A Scoping Review.Asian Pacific journal of cancer prevention : APJCP · 2026Article
- Diagnostic efficacy of VELscope in oral potentially malignant disorders: a systematic review and meta-analysis.Frontiers in oral health · 2026Review
- Diagnostic Performance of Autofluorescence for Oral Lesions: A Comparison Between a Postgraduate and an Expert Clinician.Dentistry journal · 2025Article
- In-vivo non-contact multispectral oral disease image dataset with segmentation.Scientific data · 2024Article
- Article
- Characteristics of Clinically Classified Oral Lichen Planus in Optical Coherence Tomography: A Descriptive Case-Series Study.Diagnostics (Basel, Switzerland) · 2023Article
- Diagnostic value of objective VELscope fluorescence methods in distinguishing oral cancer from oral potentially malignant disorders (OPMDs).Translational cancer research · 2022Article
- Complementarity of Photo-Biomodulation, Surgical Treatment, and Antibiotherapy for Medication-Related Osteonecrosis of the Jaws (MRONJ).Medicina (Kaunas, Lithuania) · 2021Article
- Healthcare Professional in the Loop (HPIL): Classification of Standard and Oral Cancer-Causing Anomalous Regions of Oral Cavity Using Textural Analysis Technique in Autofluorescence Imaging.Sensors (Basel, Switzerland) · 2020Article
- To Evaluate the Efficacy of Tissue Autofluorescence (Velscope) in the Visualization of Oral Premalignant and Malignant Lesions among High-Risk Population Aged 18 Years and Above in Haroli Block of Una, Himachal Pradesh.Journal of International Society of Preventive & Community DentistryArticle
- Efficacy of Autofluorescence in Detection of Tobacco-associated Oral Mucosal Lesions - A Systematic Review.Annals of maxillofacial surgeryArticle
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Early diagnosis of oral cancer through visual inspection followed by histopathological confirmation is a pivotal step for reducing rates of morbidity and mortality. There are several auxiliary devices used to improve oral examination. The purpose of this cross-sectional pilot study is to evaluate the sensitivity and specificity of the Visually Enhance Lesion Scope (VelScope) system when it is used by the general dentist after a yearly oral medicine training. Thirty-five patients with oral lesions were evaluated with clinical and VelScope examination by two general dentists, one of which trained with a specific course. A comparison of the histopathological results, clinical examination, and VelScope made by both dentists was performed through statistical analysis. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) for detecting oral potentially malignant disorders (OPMDs) are 53.3%, 65%, 53.3%, 76.5% for unskilled dentist, 73.3%, 65%, 61.1%, 76.5% for skilled clinician. When both examiners use VelScope the values are 53.3%, 70%, 57.1%, 66.7% for unskilled general dentist (u-GD), 86.7%, 90%, 86.7%, 90% for skilled general dentist (s-GD). Improvement of a skilled general dentist for detecting malignancies is higher than inexperienced examiner when using VelScope. VelScope alone is unable to improve the general dentist's ability to detect malignancies, but it could be a useful adjunctive device for clinicians when a focused training program is performed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.