Evidence map›Paper›PMID 32516884›Full record

ArticleCells2020

Newcastle Disease Virus (NDV) Oncolytic Activity in Human Glioma Tumors Is Dependent on CDKN2A-Type I IFN Gene Cluster Codeletion.

Noemi García-Romero, Irina Palacín-Aliana, Susana Esteban-Rubio, Rodrigo Madurga, Sergio Rius-Rocabert, Josefa Carrión-Navarro, Jesús Presa, Sara Cuadrado-Castano, Pilar Sánchez-Gómez, Adolfo García-Sastre and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 34 citations in OpenAlex.

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  17. Oncolytic Viruses: Immunotherapy Drugs for Gastrointestinal Malignant Tumors.Frontiers in cellular and infection microbiology · 2022
    Review
  18. Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 3 countries.

Noemi García-RomeroFaculty of Experimental Sciences, Universidad Francisco de Vitoria, 28223 Madrid, Spain.ORCID 0000-0001-7744-8848
Irina Palacín-AlianaAtrys Health, 08025 Barcelona, Spain.
Susana Esteban-RubioFacultad de Medicina, Instituto de Medicina Molecular Aplicada (IMMA), Universidad San Pablo-CEU, 28668 Madrid, Spain.
Rodrigo MadurgaFaculty of Experimental Sciences, Universidad Francisco de Vitoria, 28223 Madrid, Spain.ORCID 0000-0002-1381-2599
Sergio Rius-RocabertFacultad de Medicina, Instituto de Medicina Molecular Aplicada (IMMA), Universidad San Pablo-CEU, 28668 Madrid, Spain.
Josefa Carrión-NavarroFaculty of Experimental Sciences, Universidad Francisco de Vitoria, 28223 Madrid, Spain.
Jesús PresaIndependent researcher, 28003 Madrid, Spain.ORCID 0000-0002-6511-7811
Sara Cuadrado-CastanoDepartment of Microbiology, Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0002-9400-746X
Pilar Sánchez-GómezNeurooncology Unit, Instituto de Salud Carlos III-UFIEC, 28220 Madrid, Spain.
Adolfo García-SastreDepartment of Microbiology, Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0002-6551-1827
Estanislao Nistal-VillanFacultad de Medicina, Instituto de Medicina Molecular Aplicada (IMMA), Universidad San Pablo-CEU, 28668 Madrid, Spain.
Angel Ayuso-SacidoFaculty of Experimental Sciences, Universidad Francisco de Vitoria, 28223 Madrid, Spain.ORCID 0000-0003-3919-5880
Universidad Francisco de Vitoria · ESUniversidad San Pablo CEU · ESEcorys (Netherlands) · NLIcahn School of Medicine at Mount Sinai · USInstituto de Salud Carlos III · ESTisch Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioblastoma (GBM) is the most aggressive and frequent primary brain tumor in adults with a median overall survival of 15 months. Tumor recurrence and poor prognosis are related to cancer stem cells (CSCs), which drive resistance to therapies. A common characteristic in GBM is

Indexed as

Multigene FamilyBrain NeoplasmsCyclin-Dependent Kinase Inhibitor p16GliomaHumansInterferon-betaInterferon Type IKineticsModels, BiologicalNeoplastic Stem CellsNewcastle disease virusOncolytic VirusesRecombinant ProteinsVirus ReplicationCyclin-Dependent Kinase Inhibitor p16Interferon-betaInterferon Type IRecombinant ProteinsglioblastomaInterferon INewcastle disease virus (NDV)oncolytic virotherapy

Identifiers

PMID32516884
PMCPMC7349162
OpenAlexW3033014431

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.