ArticleNanomaterials (Basel, Switzerland)2020
Considerations for and Guidance to Testing and Evaluating Migration/Release of Nanoparticles from Polymer Based Nanocomposites.
Article in Nanomaterials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 26 citations in OpenAlex.
- Analytical challenges in the assessment of intestinal fate, uptake and crossing of food-relevant nanomaterials.Mikrochimica acta · 2026Review
- Do We Need Titanium Dioxide (TiOToxics · 2025Review
- Metal Oxide Nanoparticles in Food Packaging and Their Influence on Human Health.Foods (Basel, Switzerland) · 2023Review
- Application of silver-based biocides in face masks intended for general use requires regulatory control.The Science of the total environment · 2023Article
- Titanium dioxide particles frequently present in face masks intended for general use require regulatory control.Scientific reports · 2022Article
- Guidance on risk assessment of nanomaterials to be applied in the food and feed chain: human and animal health.EFSA journal. European Food Safety Authority · 2021Article
- Changing the Vision in Smart Food Design Utilizing the Next Generation of Nanometric Delivery Systems for Bioactive Compounds.Foods (Basel, Switzerland) · 2020Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The use of nanoadditives in food contact materials requires risk assessment to ensure consumers' safety. The evaluation of health risk is based on the combination of two elements: hazard and exposure. For nanomaterials (NM) used as additives in nanocomposites, the exposure is directly linked to the level of migration or release of the NM into the food. In principle, appropriate methods for experimental determination and theoretical estimation of migration are available but need diligent considerations to avoid erroneous conclusions from the measured data. We propose a comprehensive test scheme based on these methods, starting with characterization of the nanomaterial itself and when incorporated in the polymer. These data form the basis for making a decision whether migration of the NM can be excluded by migration theoretical considerations or if experimental migration testing and/or abrasion testing for mechanical release should be carried out. Guidance to and considerations for each of these steps and regarding the applicable methods are discussed. In conclusion, the results will provide a basis for risk assessment, either directly when exposure of consumers to the nanomaterials can be excluded or will be very low or, in the case of evidenced exposure, in combination with then needed toxicological data.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.