ArticleDementia and geriatric cognitive disorders2020
Eye Tracking Analysis of Visual Cues during Wayfinding in Early Stage Alzheimer's Disease.
Article in Dementia and geriatric cognitive disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Virtual Reality and Serious Videogame-Based Instruments for Assessing Spatial Navigation in Alzheimer's Disease: A Systematic Review of Psychometric Properties.Neuropsychology review · 2025Pooled it
- A Cluster Randomized Controlled Trial of Visual Cues, Signage, and Spaced Retrieval for Wayfinding Within Long-Term Care Communities.The Gerontologist · 2025Trial
- Alzheimer's disease digital biomarkers multidimensional landscape and AI model scoping review.NPJ digital medicine · 2025Article
- Quantifying Mild Cognitive Impairments in Older Adults Using Multi-modal Wearable Sensor Data in a Kitchen Environment.medRxiv : the preprint server for health sciences · 2025Article
- Altered interactions between attentional networks in older adults with mild cognitive impairment.Heliyon · 2025Article
- Wayfinding behavioral patterns of seniors with dementia: two exploratory case studies.Frontiers in dementia · 2025Article
- Article
- Amyloid-β Deposition Predicts Grocery Shopping Performance in Older Adults Without Cognitive Impairment.Journal of Alzheimer's disease : JAD · 2024Article
- Research Progress of Eye Movement Analyses and its Detection Algorithms in Alzheimer's Disease.Current Alzheimer research · 2024Review
- Digital Marker for Early Screening of Mild Cognitive Impairment Through Hand and Eye Movement Analysis in Virtual Reality Using Machine Learning: First Validation Study.Journal of medical Internet research · 2023Article
- Pediatricians' focus of sight at pain assessment during a neonatal heel puncture.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2023Article
- The Potential of Naturalistic Eye Movement Tasks in the Diagnosis of Alzheimer's Disease: A Review.Brain sciences · 2021Review
- Mapping the Evolutions and Trends of Literature on Wayfinding in Indoor Environments.European journal of investigation in health, psychology and education · 2021Review
- The Feasibility of Using Virtual Reality and Eye Tracking in Research With Older Adults With and Without Alzheimer's Disease.Frontiers in aging neuroscience · 2021Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
introductionPersons with Alzheimer's disease (AD) have profound impairment in wayfinding, potentially related to a deficit in visual attention and selection of relevant environmental information. This study sought to determine differences in visual attention to salient visual cues and nonsalient cues (building features) in older adults with and without AD during active wayfinding in a large-scale, virtual reality spatial task.
methodsFifteen subjects (7 with AD and 8 controls without AD) were asked to find their way repeatedly during 10 trials in a virtual simulation of a senior retirement community. Subjects wore eye tracking glasses to capture visual fixations while wayfinding. The least square means (LSMs) and their standard errors (SEs) for percentage of fixations and duration of fixations on salient and nonsalient cues were estimated from the linear mixed effects models and compared by group (AD or control) and cue type.
resultsThe group by cue type interaction was significant for both percentage of fixations (F(1, 13) = 6.79, p = 0.02) and duration of fixations (F(1, 13) = 4.87, p = 0.04). The AD group had significantly lower percentages of fixations on salient cues, LSM = 57.91 (SE = 2.44), compared to controls, LSM = 66.40 (SE = 2.19); p = 0.03. Persons with AD had a higher percentage of fixations on building features, LSM = 31.65 (SE = 2.18), than controls, LSM = 24.54 (SE = 1.95); p = 0.02. Shorter durations of fixations on salient cues were experienced by the AD group, LSM = 38.89 (SE = 1.69), than the control group, LSM = 44.69 (SE = 1.55); p = 0.02. DISCUSSION/
conclusionIndividuals with AD may have difficulty selecting relevant information for wayfinding as compared to normally aging individuals and attend more frequently than controls to irrelevant information. This may help explain the wayfinding difficulties seen in AD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.