Evidence map›Paper›PMID 32516723›Full record

ReviewCurrent opinion in insect science2020

Advances in oral RNAi for disease vector mosquito research and control.

Rachel M Wiltshire, Molly Duman-Scheel

Abstract readReview
In one paragraph

Review in Current opinion in insect science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Review
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  17. Review
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  19. mBio · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Rachel M WiltshireDepartment of Medical and Molecular Genetics, Indiana University School of Medicine, 1234 N. Notre Dame Ave, South Bend, IN 46617, USA; Eck Institute for Global Health, University of Notre Dame, Notre Dame, IN 46556, USA.
Molly Duman-ScheelDepartment of Medical and Molecular Genetics, Indiana University School of Medicine, 1234 N. Notre Dame Ave, South Bend, IN 46617, USA; Eck Institute for Global Health, University of Notre Dame, Notre Dame, IN 46556, USA; Department of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556, USA. Electronic address: mscheel@nd.edu.

Funding

Development of Yeast Interfering RNA Larvicides Targeting Aedes aegyptiR21AI128116 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI SCHEEL, MOLLY DUMAN, SEVERSON, DAVID W · 2017 to 2018
$444k
NIAID NIH HHS R21 AI128116
6 · The paper itself

Abstract

Mosquito vectors in the genera Anopheles, Aedes, and Culex transmit a variety of medically important pathogens. Current vector control tools are reaching the limits of their effectiveness, necessitating the introduction of innovative vector control technologies. RNAi, which facilitates functional characterization of mosquito genes in the laboratory, could one day be applied as a new method of vector control. Recent advances in the oral administration of microbial-based systems for delivery of species-specific interfering RNA pesticides to mosquitoes may facilitate translation of this technology to the field. Oral RNAi-based pesticides represent a new class of biorational pesticides that could combat increased global incidence of insecticide resistance and which could one day become critical components of integrated human disease vector mosquito control programs.

Indexed as

RNA InterferenceAnimalsCulicidaeMosquito ControlMosquito Vectors

Identifiers

PMID32516723
PMCPMC8718359

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.