ArticleThe British journal of radiology2020
Impact of dosimetric differences between CT and MRI derived target volumes for external beam cervical cancer radiotherapy.
Article in The British journal of radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 9 citations in OpenAlex.
- Dosimetric evaluation of field parameters in VMAT for cervical cancer with inguinal lymphatic drainage extension.Scientific reports · 2025Article
- Generalizable transfer learning of automated tumor segmentation from cervical cancers toward a universal model for uterine malignancies in diffusion-weighted MRI.Insights into imaging · 2023Article
- MRI is more valuable than CT in the diagnosis of cervical cancer.American journal of translational research · 2023Article
- The impact of an educational tool in cervix image registration across three imaging modalities.The British journal of radiology · 2022Article
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Authors and funding
10 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe use of MRI is becoming more prevalent in cervical cancer external beam radiotherapy (RT). The aim of this study was to investigate the impact of dosimetric differences between CT and MRI-derived target volumes for cervical cancer external beam RT.
methodsAn automated planning technique for volumetric modulated arc therapy was developed. Two automated planning plans were generated for 18 cervical cancer patients where planning target volumes (PTVs) were generated based on CT or MRI data alone. Dose metrics for planning target volumes and organs at risk (OARs) were compared to analyse any differences based on imaging modality.
resultsAll treatment plans were clinically acceptable. Bladder doses (V40) were lower in MRI-based plans (
conclusionsThe dosimetric differences of CT- and MRI-based contouring variability for this study was small. CT remains the standard imaging modality for volume delineation for these patients. ADVANCES IN KNOWLEDGE: This is the first study to evaluate the dosimetric implications of imaging modality on target and OAR doses in cervical cancer external beam RT.
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