SynthesisPloS one2020
Effect of transcranial direct-current stimulation on cognitive function in stroke patients: A systematic review and meta-analysis.
Synthesis in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Effect of non-invasive brain stimulation on post-stroke cognitive impairment: a meta-analysis.Frontiers in neurology · 2024Pooled it
- Efficacy and hematological markers of tDCS combined with aerobic exercise in improving executive function in patients with PSCI.Journal of neuroengineering and rehabilitation · 2026Trial
- tDCS and Speech Therapy in Aphasia Treatment: A Multicenter Comparative Study of Efficacy.Medical science monitor : international medical journal of experimental and clinical research · 2025Trial
- Combined Effect of HF-rTMS and Whole-Body Vibration Exercise on Cognitive Efficiency in Esports Players With or Without Sedentary Behaviors: A Randomized Controlled Trial.Brain and behavior · 2025Trial
- The effect of transcranial direct current stimulation and inhibitory control training on depression and anxiety among post-stroke individuals.BMC neurology · 2025Trial
- Cognitive changes in post-stroke depression patients undergoing treatment with transcranial direct current stimulation (tDCS): an exploratory, ancillary analysis of a randomized, sham-controlled clinical trial.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2025Trial
- Effects of tDCS on Cognitive Function in MCAO/R Rats by Regulating Mitochondrial Autophagy Mediated by the PINK1/Parkin Signaling Pathway.Neurochemical research · 2026Article
- Knowledge, attitudes, and practices of Chinese neurologists toward transcranial direct current stimulation.BMC neurology · 2026Article
- A protocol to optimize non-invasive brain stimulation for post-stroke rehabilitation.MethodsX · 2025Article
- Effect of Transcranial Direct Current Stimulation on Memory and Emotional Recovery in Patients with Stroke and Traumatic Brain Injury: A Prospective, Multicenter, Interventional Pilot Study.Journal of clinical medicine · 2025Article
- Transcranial direct current stimulation in individuals with severe traumatic brain injury in the subacute phase: a case series.Frontiers in human neuroscience · 2025Article
- Multifocal transcranial electrical stimulation to enhance cognitive functions: a systematic review.Frontiers in neuroscience · 2025Review
- Transcranial Direct Current Stimulation and Mindfulness for Cognitive and Mood Recovery in Stroke Survivors: A Pilot Randomized Controlled Study.Stroke research and treatment · 2025Article
- Review
- Personalized high-definition transcranial direct current stimulation improves cognition following carbon monoxide poisoning induced amnesia: A case report.Journal of the International Neuropsychological Society : JINS · 2024Article
- Effect of tDCS combined with virtual reality for post-stroke cognitive impairment: a randomized controlled trial study protocol.BMC complementary medicine and therapies · 2024Article
- Transcranial Direct Current Stimulation to Ameliorate Post-Stroke Cognitive Impairment.Brain sciences · 2024Review
- Article
- Meta-modeling the effects of anodal left prefrontal transcranial direct current stimulation on working memory performance.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Investigating the neural mechanisms of transcranial direct current stimulation effects on human cognition: current issues and potential solutions.Frontiers in neuroscience · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTranscranial direct-current stimulation (tDCS) is a noninvasive approach that can alter brain excitability. Several studies have shown the effectiveness of tDCS in improving language and movement function in stroke patients. However, the effect of tDCS on cognitive function after stroke remains uncertain.
methodsWe searched Medline, Embase, the Cochrane Central Register of Controlled Trials (CENTRAL), the China National Knowledge Infrastructure, the China Science and Technology Journal Database, and the Wanfang Data Knowledge Service Platform from inception to April 2, 2019. Two reviewers independently screened the studies, extracted the data, and evaluated the quality of the included studies using the Cochrane Collaboration Risk of Bias Tool. All statistical analyses were performed in RevMan 5.3, and the mean difference (MD) or standard mean difference (SMD) were used as the pooled statistics.
resultsFifteen studies involving 820 participants were included. When compared with passive tDCS, anodal tDCS was associated with improved general cognitive performance as examined by the Minimum Mental State Examination or Montreal Cognitive Assessment (SMD = 1.31, 95% CI 0.91-1.71, P < 0.00001), attention performance (SMD = 0.66, 95% CI 0.11-1.20, P = 0.02). There was no significant difference in memory performance (SMD = 0.41, 95% CI -0.67-1.50, P = 0.46).
conclusionstDCS is likely to be effective for patients with cognitive impairment after stroke. The evidence for different effects based on population characteristics and stimulation methods was limited, but a real effect cannot be ruled out. More high-quality research in this field is required to determine the potential benefits of tDCS in the treatment of cognitive deficits after stroke and to establish the optimal treatment program.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.