Evidence map›Paper›PMID 32515168›Full record

ArticleInternational journal of immunogenetics2020

Clonal haematopoiesis and COVID-19: A possible deadly liaison.

Velizar Shivarov, Milena Ivanova

Abstract read
In one paragraph

Article in International journal of immunogenetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Clonal haematopoiesis and COVID-19: A possible deadly liaison.International journal of immunogenetics · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Velizar ShivarovDepartment of Clinical Hematology, Sofiamed University Hospital, Sofia, Bulgaria.ORCID https://orcid.org/0000-0001-5362-7999
Milena IvanovaDepartment of Clinical Immunology, University Hospital Alexandrovska, Medical University Sofia, Sofia, Bulgaria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We provide evidence for a linear correlation between the frequency of clonal haematopoiesis and COVID-19 mortality rate. We discuss the mechanistic explanations for this association mediated by a pathological inflammatory response. Our hypothesis can be tested in COVID-19-infected patients and eventually lead to new approaches to risk stratification and therapy.

Indexed as

Aged, 80 and overAge FactorsAgingBetacoronavirusClonal Selection, Antigen-MediatedCoronavirus InfectionsCOVID-19HematopoiesisHumansPandemicsPneumonia, ViralSARS-CoV-2ARDSclonal haematopoiesisCOVID-19inflammationSARS-CoV-2

Identifiers

PMID32515168
PMCPMC7300620

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.