ArticleTechniques in coloproctology2020
A low incidence of perineal hernia when using a biological mesh after extralevator abdominoperineal excision with or without pelvic exenteration or distal sacral resection in locally advanced rectal cancer patients.
Article in Techniques in coloproctology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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11 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Meta-analysis of biological mesh reconstruction versus primary perineal closure after abdominoperineal excision of rectal cancer.International journal of colorectal disease · 2021Pooled it
- A new surgical approach of direct perineal wound full-thick closure for perineal wound of abdominoperineal resection for rectal carcinoma: A prospective cohort trial.International wound journal · 2020Trial
- Perineal infection and risk factors following extralevator abdominoperineal excision and reconstruction with an absorbable synthetic prosthesis.Updates in surgery · 2026Observational
- Bony pelvic resection is a risk factor for pelvic abscess after total pelvic exenteration for pelvic malignancies.Surgery today · 2026Article
- Perineal hernia following extra-levator abdominoperineal resection: prevalence, associated risk factors and types of perineal closure. a single-centre descriptive study.Hernia : the journal of hernias and abdominal wall surgery · 2026Article
- Curative surgery enabled by radiotherapy in rectal cancer: A case report.Oncology letters · 2026Article
- Anterior perineal hernia - A case report of a rare complication after pelvic exenteration.International journal of surgery case reports · 2024Article
- Short- and mid-term outcomes of abdominoperineal resection with perineal mesh insertion: a single-centre experience.International journal of colorectal disease · 2023Article
- [Reconstruction of oncological defects of the perianal region].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021Article
- [Prophylaxis of parastomal, perineal and incisional hernias in colorectal surgery].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021Review
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5 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundExtralevator abdominoperineal excision (ELAPE), abdominoperineal excision (APE) or pelvic exenteration (PE) with or without sacral resection (SR) for locally advanced rectal cancer leaves a significant defect in the pelvic floor. At first, this defect was closed primarily. To prevent perineal hernias, the use of a biological mesh to restore the pelvic floor has been increasing. The aim of this study, was to evaluate the outcome of the use of a biological mesh after ELAPE, APE or PE with/without SR.
methodsA retrospective study was conducted on patients who had ELAPE, APE or PE with/without SR with a biological mesh (Permacol™) for pelvic reconstruction in rectal cancer in our center between January 2012 and April 2015. The endpoints were the incidence of perineal herniation and wound healing complications.
resultsData of 35 consecutive patients [22 men, 13 women; mean age 62 years (range 31-77 years)] were reviewed. Median follow-up was 24 months (range 0.4-64 months). Perineal hernia was reported in 3 patients (8.6%), and was asymptomatic in 2 of them. The perineal wound healed within 3 months in 37.1% (n = 13), within 6 months in 51.4% (n = 18) and within 1 year in 62.9% (n = 22). In 17.1% (n = 6), the wound healed after 1 year. It was not possible to confirm perineal wound healing in the remaining 7 patients (20.0%) due to death or loss to follow-up. Wound dehiscence was reported in 18 patients (51.4%), 9 of whom needed vacuum-assisted closure therapy, surgical closure or a flap reconstruction.
conclusionsClosure of the perineal wound after (EL)APE with a biological mesh is associated with a low incidence of perineal hernia. Wound healing complications in this high-risk group of patients are comparable to those reported in the literature.
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