Evidence map›Paper›PMID 32514863›Full record

ArticleMolecular neurobiology2020

Increased Oxidative Stress Toxicity and Lowered Antioxidant Defenses in Temporal Lobe Epilepsy and Mesial Temporal Sclerosis: Associations with Psychiatric Comorbidities.

Michael Maes, Thitiporn Supasitthumrong, Chusak Limotai, Ana Paula Michelin, Andressa Keiko Matsumoto, Laura de Oliveira Semão, João Victor de Lima Pedrão, Estefânia Gastaldello Moreira, Andre F Carvalho, Sunee Sirivichayakul and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 32 citations in OpenAlex.

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  10. Hydroalcoholic Leaf Extract ofOxidative medicine and cellular longevity · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 5 countries.

Michael MaesDepartment of Psychiatry, Faculty of Medicine, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
Thitiporn SupasitthumrongDepartment of Psychiatry, Faculty of Medicine, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
Chusak LimotaiChulalongkorn Comprehensive Epilepsy Center of Excellence (CCEC), The Thai Red Cross Society; Division of Neurology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Ana Paula MichelinHealth Sciences Graduate Program, Health Sciences Center, State University of Londrina, Londrina, PR, Brazil.
Andressa Keiko MatsumotoHealth Sciences Graduate Program, Health Sciences Center, State University of Londrina, Londrina, PR, Brazil.
Laura de Oliveira SemãoHealth Sciences Graduate Program, Health Sciences Center, State University of Londrina, Londrina, PR, Brazil.
João Victor de Lima PedrãoHealth Sciences Graduate Program, Health Sciences Center, State University of Londrina, Londrina, PR, Brazil.
Estefânia Gastaldello MoreiraHealth Sciences Graduate Program, Health Sciences Center, State University of Londrina, Londrina, PR, Brazil.
Andre F CarvalhoDepartment of Psychiatry, University of Toronto, Toronto, ON, Canada.
Sunee SirivichayakulFaculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Décio Sabbatini BarbosaHealth Sciences Graduate Program, Health Sciences Center, State University of Londrina, Londrina, PR, Brazil.
Buranee KanchanatawanDepartment of Psychiatry, Faculty of Medicine, King Chulalongkorn Memorial Hospital, Bangkok, Thailand. drburanee@gmail.com.ORCID http://orcid.org/0000-0002-5387-8867
Universidade Estadual de Londrina · BRKing Chulalongkorn Memorial Hospital · THCentre for Addiction and Mental Health · CAChulalongkorn University · THDeakin University · AUThai Red Cross Society · TH

Funding

Ratchadapisek Research Fund RA 57/024
6 · The paper itself

Abstract

Oxidative stress toxicity (OSTOX), as well as lowered antioxidant defenses (ANTIOX), plays a role in temporal lobe epilepsy (TLE). Nevertheless, the associations between OSTOX/ANTIOX and psychiatric comorbidities in TLE are largely unknown. Thus, this study examines plasma malondialdehyde (MDA), lipid hydroperoxides (LOOH), advanced oxidation protein products (AOPP), nitric oxide metabolites (NO

Indexed as

AdultAntioxidantsEpilepsy, Temporal LobeFemaleHumansMajor Depressive DisorderMaleMiddle AgedNitric OxideNitrosative StressOxidative StressPsychotic DisordersAntioxidantsNitric OxideInflammationMajor depressionNeuroimmunomodulationNeurotoxicityOxidative stressSchizophreniaTemporal lobe epilepsy

Identifiers

PMID32514863
OpenAlexW3002049796

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.