Evidence map›Paper›PMID 32514775›Full record

ArticleWorld journal of surgery2020

A New Synthetic Conduit for the Treatment of Peripheral Nerve Injuries.

Selman Uranues, Georg Bretthauer, Gordana Tomasch, Dietmar Rafolt, Doris Nagele-Moser, Andrea Berghold, Reinhold Kleinert, Ivo Justich, Jörg Waldert, Horst Koch

Open access · hybridAbstract read
In one paragraph

Article in World journal of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Natural-Based Biomaterials for Peripheral Nerve Injury Repair.Frontiers in bioengineering and biotechnology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Selman UranuesSection for Surgical Research, Department of Surgery, Medical University of Graz, Auenbruggerplatz 29, 8036, Graz, Austria. selman.uranues@medunigraz.at.
Georg BretthauerInstitute for Automation and Applied Informatics, Karlsruhe Institute of Technology, 76344, Eggenstein-Leopoldshafen, Germany.
Gordana TomaschSection for Surgical Research, Department of Surgery, Medical University of Graz, Auenbruggerplatz 29, 8036, Graz, Austria.
Dietmar RafoltCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, 1090, Vienna, Austria.
Doris Nagele-MoserSection for Surgical Research, Department of Surgery, Medical University of Graz, Auenbruggerplatz 29, 8036, Graz, Austria.
Andrea BergholdInstitute for Medical Informatics, Statistics and Documentation, Medical University of Graz, 8036, Graz, Austria.
Reinhold KleinertInstitute of Pathology, Medical University of Graz, 8036, Graz, Austria.
Ivo JustichClinical Division of Plastic, Aesthetic and Reconstructive Surgery, Medical University of Graz, 8036, Graz, Austria.
Jörg WaldertState Hospital for Neurology and Psychiatrics, 8055, Graz, Austria.
Horst KochClinical Division of Plastic, Aesthetic and Reconstructive Surgery, Medical University of Graz, 8036, Graz, Austria.
Medical University of Graz · ATGraz University Hospital · ATKarlsruhe Institute of Technology · DEMedical University of Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeripheral nerve defects (PND) often cause lifelong physical disability, and the available treatment options are often not satisfactory. PND are usually bridged with an autologous nerve transplant or a nerve guidance conduit (NGC), when coaptation as preferred technique is not possible. The aim of this experimental study was to determine the effectiveness of a novel NGC for regeneration in the treatment of PND. MATERIALS AND

methodsA conduit made of gelatin with an innovative interior structure was tested for the repair of a 6-mm gap versus direct microsurgical suture repair without gap.

resultsWe found that bridging the defect with this conduit was as effective as direct microsurgical coaptation without a defect.

conclusionsThis nerve conduit, effective in bridging neural defects, appears as an alternative to autologous nerve grafts, avoiding the problems related to nerve graft harvesting, host-donor differences in diameter, mismatches in number and pattern of fascicles, cross-sectional shape and area, and morbidity of the donor area.

Indexed as

Nerve RegenerationProstheses and ImplantsAnimalsAtrophyEvoked Potentials, MotorGait AnalysisGelatinModels, AnimalMusclesNeurosurgical ProceduresPeripheral Nerve InjuriesProsthesis DesignRandom AllocationSciatic NerveSwineSwine, MiniatureGelatinTitanium

Identifiers

PMID32514775
PMCPMC7458941
OpenAlexW3033713738

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.