Evidence map›Paper›PMID 32514330›Full record

ArticleEvoDevo2020

Transcription factors underlying wing margin color patterns and pupal cuticle markings in butterflies.

Robert D Reed, Jayne E Selegue, Linlin Zhang, Craig R Brunetti

Abstract read
In one paragraph

Article in EvoDevo, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Robert D ReedDepartment of Ecology and Evolutionary Biology, Cornell University, 215 Tower Road, Ithaca, NY 14853-7202 USA.
Jayne E SelegueSchool of Pharmacy, University of Wisconsin, 777 Highland Ave, Madison, WI 53705 USA.
Linlin ZhangDepartment of Ecology and Evolutionary Biology, Cornell University, 215 Tower Road, Ithaca, NY 14853-7202 USA.
Craig R BrunettiDepartment of Biology, Trent University, 1600 East Bank Dr., Peterborough, ON K9J 7B8 Canada.ORCID 0000-0001-6166-1628

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe diversity of butterfly color patterns can be attributed to a relatively small number of pattern elements that are homologous across Lepidoptera. Although genes involved in patterning some of these elements have been identified, the development of several major elements remains poorly understood. To identify genes underlying wing pupal cuticle markings and wing margin color patterns, we examined expression of the candidate transcription factors Engrailed/Invected (En/Inv), Distal-less (Dll), Cubitus interruptus (Ci), and Spalt in two nymphalids:

resultsWe found that En/Inv, Dll, and Ci mark domains on the

conclusionOur observations support the model that a core set of regulatory genes are redeployed multiple times, and in multiple roles, during butterfly wing pattern development. Of these genes,

Indexed as

Bicyclus anynanaButterflyDistal-lessEyespotJunonia coeniaMarginal bandsSpaltWing patterning

Identifiers

PMID32514330
PMCPMC7254719

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.