Evidence map›Paper›PMID 32514312›Full record

ArticleBiotechnology for biofuels2020

Purification and immobilization of engineered glucose dehydrogenase: a new approach to producing gluconic acid from breadwaste.

Pinar Karagoz, Ravneet Mandair, Jinesh Cherukkattu Manayil, Jai Lad, Katie Chong, Georgios Kyriakou, Adam F Lee, Karen Wilson, Roslyn M Bill

Open access · goldAbstract read
In one paragraph

Article in Biotechnology for biofuels, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Pinar KaragozSchool of Life and Health Sciences, Aston University, Birmingham, B4 7ET UK.
Ravneet MandairSchool of Life and Health Sciences, Aston University, Birmingham, B4 7ET UK.
Jinesh Cherukkattu ManayilEuropean Bioenergy Research Institute (EBRI), Aston University, Birmingham, B4 7ET UK.
Jai LadEuropean Bioenergy Research Institute (EBRI), Aston University, Birmingham, B4 7ET UK.
Katie ChongEuropean Bioenergy Research Institute (EBRI), Aston University, Birmingham, B4 7ET UK.
Georgios KyriakouDepartment of Chemical Engineering, University of Patras, 265 04 Patras, Greece.
Adam F LeeApplied Chemistry & Environmental Science, School of Science, RMIT University, Melbourne, VIC 3000 Australia.
Karen WilsonApplied Chemistry & Environmental Science, School of Science, RMIT University, Melbourne, VIC 3000 Australia.
Roslyn M BillSchool of Life and Health Sciences, Aston University, Birmingham, B4 7ET UK.ORCID 0000-0003-1331-0852
Aston University · GBRMIT University · AUUniversity of Patras · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPlatform chemicals are essential to industrial processes. Used as starting materials for the manufacture of diverse products, their cheap availability and efficient sourcing are an industrial requirement. Increasing concerns about the depletion of natural resources and growing environmental consciousness have led to a focus on the economics and ecological viability of bio-based platform chemical production. Contemporary approaches include the use of immobilized enzymes that can be harnessed to produce high-value chemicals from waste.

resultsIn this study, an engineered glucose dehydrogenase (GDH) was optimized for gluconic acid (GA) production.

conclusionsThis study demonstrates the feasibility of enzymatically converting BWH to GA: immobilizing GDH on MM-SBA-15 renders the enzyme more stable and permits its multiple reuse.

Indexed as

EnzymeImmobilizationRecombinant proteinWaste valorization

Identifiers

PMID32514312
PMCPMC7268246
OpenAlexW3025209599

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.