Evidence map›Paper›PMID 32514229›Full record

ArticleTropical medicine and health2020

Determinants of neonatal mortality at neonatal intensive care unit in Northeast Ethiopia: unmatched case-control study.

Abebaw Yeshambel Alemu, Getaneh Mulualem Belay, Mengistu Berhanu, Biniam Minuye

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Tropical medicine and health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04947215 (The Association Between LPCAT1 Genetic Polymorphism and Stress Biomarkers in Neonatal Respiratory Distress Syndrome), which is not on this map. Cited by 20 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 4 pooled it
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04947215 unknown statusnot on this mapstarted 2021, after this paper: background citation

The Association Between LPCAT1 Genetic Polymorphism and Stress Biomarkers in Neonatal Respiratory Distress Syndrome

TypeobservationalSponsorAssiut UniversityRan2021 to 2022Enrolled160ConditionsNeonatal Respiratory DistressArmsstress biomarkers
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 4 syntheses or guidelines pooled it, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Abebaw Yeshambel AlemuDepartment of Nursing, College of Health Science, Debre Tabor University, Debre Tabor, Ethiopia.
Getaneh Mulualem BelayDepartment of Pediatric and Child Health Nursing, School of Nursing, College of Medicine and Health Sciences, University of Gondar, P.O.Box:196, Gondar, Ethiopia.
Mengistu BerhanuDepartment of Pediatric and Child Health Nursing, School of Nursing, College of Medicine and Health Sciences, University of Gondar, P.O.Box:196, Gondar, Ethiopia.
Biniam MinuyeDepartment of Nursing, College of Health Science, Debre Tabor University, Debre Tabor, Ethiopia.
Debre Tabor University · ETUniversity of Gondar · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGlobally, in 2016, about 38% and 3% of all neonatal death were recorded in sub-Saharan Africa and Ethiopia, respectively. In the same year, 47 neonates out of 1000 live births were not surviving in the first 28 days of age in the Amhara region, Ethiopia. Despite the highest burden of neonatal death in the region, specific or the proximate determinants of neonatal death in the neonatal intensive care unit were not well identified.

objectiveThis study aimed to identify the determinants of neonatal mortality at neonatal intensive care unit in Dessie Referral Hospital, Northeast Ethiopia.

methodsAn institution-based unmatched case-control study was conducted on neonates admitted to the neonatal intensive care unit of Dessie Referral Hospital, from January 1, 2016, to December 30, 2017. A total of 390 charts (130 cases and 260 controls) were selected by simple random sampling technique. The data were abstracted from the facility-based data abstraction form. A binary logistic regression analysis was fitted to identify the determinants of neonatal mortality.

resultsPregnancy-induced hypertension (AOR = 4.57; 95% CI 1.45-14.43), prolonged rupture of membrane (AOR = 2.04; 95% CI 1.13-3.68), very low birth weight (AOR = 7.00; 95% CI 2.10-23.35), and low birth weight (AOR = 2.12; 95% CI 1.10-4.20) were identified factors. Moreover, respiratory distress syndrome (AOR = 3.61; 95% CI 1.10-12.04), perinatal asphyxia (AOR = 2.27; 95% CI 1.18-4.39), meconium aspiration syndrome (AOR = 2.35; 95% CI 1.12-4.97), and infection (AOR = 2.26; 95% CI 1.34-3.82) were also significantly associated with neonatal death.

conclusionsPregnancy-induced hypertension, prolonged rupture of membrane, low birth weight, respiratory distress syndrome, perinatal asphyxia, meconium aspiration syndrome, and infections were the major determinants of neonatal mortality. Therefore, special attention will be given to small and sick babies. Moreover, early anticipation of complications and management of mothers who had pregnancy-induced hypertension and prolonged rupture of the membrane would save neonates.

Indexed as

Neonatal factorsNeonatal intensive care unitNeonatal mortalityNortheast Ethiopia

Identifiers

PMID32514229
PMCPMC7268585
OpenAlexW3033856428

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.