ArticleNature medicine2020
A single-cell atlas of the peripheral immune response in patients with severe COVID-19.
Open access · bronzeAbstract read
In one paragraph
Article in Nature medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1,074 papers, 4 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
1,074citing papers in PubMed, 4 pooled it
34.5field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1,074 citing papers in PubMed, 4 syntheses or guidelines pooled it, 1,672 citations in OpenAlex.
- Single-cell RNA sequencing offers novel perspectives in viral infection research.Frontiers in cellular and infection microbiology · 2026Pooled it
- Neurological Manifestations of SARS-CoV-2.Viruses · 2025Pooled it
- Systemic cytokines drive conserved severity-associated myeloid responses across bacterial and viral infections.Communications biology · 2025Pooled it
- Single-cell transcriptome landscape of circulating CD4Cell genomics · 2024Pooled it
- Monocytes in pneumonia: Functional plasticity and innate memory (Review).International journal of molecular medicine · 2026Review
- Spatial transcriptomics unveils the in situ cellular and molecular hallmarks of the lung in fatal COVID-19.Nature communications · 2026Article
- A novel extracellular vesicle-engineered immunotherapy drug for Her2Journal of advanced research · 2026Article
- Immune dysregulation in the prostates of C57BL/6The Journal of pathology · 2026Article
- Natural killer cells against viral infection: from basic biology to immunotherapy.Precision clinical medicine · 2026Review
- Deconformer: efficient cell-type composition profiling of cfRNA across diverse cell types.Briefings in bioinformatics · 2026Article
- Article
- Single-cell and spatial transcriptomic profiling reveals distinct immune landscapes in murine lungs infected with H1N1 versus H5N1 influenza viruses.Journal of virology · 2026Article
- PathwayBench: a multi-criterion benchmark of pseudobulk pathway activity scoring methods reveals rank-window competition as a mechanism of biological signal loss in single-cell RNA-seq.Research square · 2026Article
- Interpretable deep generative ensemble learning for single-cell omics with Hydra.Molecular systems biology · 2026Article
- Hierarchical classification of immune cell transcriptomes at population-scale.bioRxiv : the preprint server for biology · 2026Article
- RepurNet: A network medicine framework for systematic drug repurposing and disease vulnerability discovery.iScience · 2026Article
- Systemic multi-omics analysis reveals interferon response heterogeneity and links lipid metabolism to immune alterations in severe COVID-19.Genome medicine · 2026Article
- Large-scale analysis of temporal gene expression variation in peripheral blood.Nature communications · 2026Article
- REACTOR: REgulon Activity analysis and Comparison Tool for single-cell transcriptOmics Research.Bioinformatics (Oxford, England) · 2026Article
- Mapping of Neutrophils in Cancers: Insights From Spatial Omics Technologies.European journal of immunology · 2026Review
1,014 more citing papers are in PubMed but not listed here.
Corrections and comments
- Update of
Authors and funding
15 authors at 3 institutions in 1 country.
Aaron J Wilk *Stanford Medical Scientist Training Program, Stanford University School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0003-1430-5852
Arjun Rustagi *Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-6921-1012
Nancy Q Zhao *Stanford Immunology Program, Stanford University School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0001-6217-854X
Jonasel RoqueDepartment of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Giovanny J Martínez-ColónDepartment of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Julia L McKechnieStanford Immunology Program, Stanford University School of Medicine, Stanford, CA, USA.
Geoffrey T IvisonStanford Immunology Program, Stanford University School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0002-3612-0069
Thanmayi RanganathDepartment of Medicine, Stanford University School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0001-9865-2119
Rosemary VergaraDepartment of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Taylor HollisDepartment of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Laura J SimpsonDepartment of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Philip GrantDepartment of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Aruna SubramanianDepartment of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Angela J RogersDepartment of Medicine, Stanford University School of Medicine, Stanford, CA, USA. ajrogers@stanford.edu.ORCID http://orcid.org/0000-0001-6969-6200
Catherine A BlishStanford Medical Scientist Training Program, Stanford University School of Medicine, Stanford, CA, USA. cblish@stanford.edu.ORCID http://orcid.org/0000-0001-6946-7627
Stanford University · USChan Zuckerberg Initiative (United States) · USStanford Medicine · US
Funding
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007365 · NIGMS · STANFORD UNIVERSITY · PI CHUA, KATRIN F · 1985 to 2021
$33.8MMOLECULAR &CELLULAR IMMUNOBIOLOGYT32AI007290 · NIAID · STANFORD UNIVERSITY · PI Sean Curtis Bendall, Olivia M Martinez · 1985 to 2026
$27.0MEMERGING INFECTIOUS DISEASEST32AI007502 · NIAID · STANFORD UNIVERSITY · PI Prasanna Jagannathan, DAVID A. RELMAN · 1995 to 2026
$6.8MUniversity of Michigan Postbaccalaureate Research Education Program (UM PREP)R25GM086262 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ALLEN, BENJAMIN · 2009 to 2024
$6.1MTargeting natural killer cells to HIV in intravenous drug usersDP1DA046089 · NIDA · STANFORD UNIVERSITY · PI BLISH, CATHERINE A · 2018 to 2022
$3.9MMetabolic derangements in ARDSK23HL125663 · NHLBI · STANFORD UNIVERSITY · PI ROGERS, ANGELA J · 2015 to 2018
$744kBurroughs Wellcome Fund (BWF) 1016687National Science Foundation (NSF) DGE-1656518NHLBI NIH HHS K23 HL125663NIAID NIH HHS T32 AI007290NIAID NIH HHS T32 AI007502NIDA NIH HHS DP1 DA046089NIGMS NIH HHS R25 GM086262NIGMS NIH HHS T32 GM007365U.S. Department of Health & Human Services | National Institutes of Health (NIH) AI007290-35U.S. Department of Health & Human Services | National Institutes of Health (NIH) T32 AI007502-23U.S. Department of Health & Human Services | National Institutes of Health (NIH) T32 GM007365-44U.S. Department of Health & Human Services | NIH | National Institute on Drug Abuse (NIDA) DP1 DA04608902Wellcome Trust
Abstract
There is an urgent need to better understand the pathophysiology of Coronavirus disease 2019 (COVID-19), the global pandemic caused by SARS-CoV-2, which has infected more than three million people worldwide
Indexed as
Coronavirus InfectionsImmunity, CellularLeukocytes, MononuclearPandemicsPneumonia, ViralAdultAgedAged, 80 and overBetacoronavirusCase-Control StudiesCOVID-19CytokinesFemaleGene Expression ProfilingHumansKiller Cells, NaturalCytokines
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.