Evidence map›Paper›PMID 32513849›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2020

Exploiting Pre-Existing CD4

Tony W Ng, Ariel S Wirchnianski, Anna Z Wec, J Maximilian Fels, Christopher T Johndrow, Kevin O Saunders, Hua-Xin Liao, John Chan, William R Jacobs, Kartik Chandran and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. PulmonaromFrontiers in cellular and infection microbiology · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. CD4Vaccines · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Tony W NgDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461.ORCID 0000-0002-2460-7929
Ariel S WirchnianskiDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461.
Anna Z WecDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461.ORCID 0000-0002-2134-2152
J Maximilian FelsDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461.
Christopher T JohndrowDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461.
Kevin O SaundersDepartment of Medicine, Duke University School of Medicine, Durham, NC 27710; and.
Hua-Xin LiaoDepartment of Medicine, Duke University School of Medicine, Durham, NC 27710; and.
John ChanDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461.
William R JacobsDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461.ORCID 0000-0003-3321-3080
Kartik ChandranDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461.
Steven A PorcelliDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461; steven.porcelli@einsteinmed.org.
Albert Einstein College of Medicine · USDuke University · US

Funding

WORD PROCESSORP30CA013330 · NCI · YESHIVA UNIVERSITY · PI STEVEN C. ALMO · 1985 to 2026
$111.2M
Immunoregulation by indoleamine 2,3-dioxygenases in tuberculosisR01AI137344 · NIAID · RBHS-NEW JERSEY MEDICAL SCHOOL · PI CHAN, JOHN R., PORCELLI, STEVEN A · 2018 to 2022
$4.0M
Modulation of Host Cell Environment by Mycobacterial PE/PPE ProteinsR01AI127711 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI LEE, SUNHEE, PORCELLI, STEVEN A · 2017 to 2021
$2.8M
High-speed/resolution whole slide scanner supported by two core facilitiesS10OD019961 · OD · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI CONDEELIS, JOHN S · 2015 to 2015
$326k
NCI NIH HHS P30 CA013330NIAID NIH HHS R01 AI127711NIAID NIH HHS R01 AI137344NIH HHS S10 OD019961
6 · The paper itself

Abstract

The continuing emergence of viral pathogens and their rapid spread into heavily populated areas around the world underscore the urgency for development of highly effective vaccines to generate protective antiviral Ab responses. Many established and newly emerging viral pathogens, including HIV and Ebola viruses, are most prevalent in regions of the world in which

Indexed as

AcyltransferasesAnimalsAntibodies, ViralAntibody FormationAntigens, BacterialBacterial ProteinsCD4-Positive T-LymphocytesDisease Models, AnimalEbola VaccinesEbolavirusFemaleHemorrhagic Fever, EbolaHumansImmunoglobulin GLymphocyte ActivationMiceAcyltransferasesAntibodies, Viralantigen 85B, Mycobacterium tuberculosisAntigens, BacterialBacterial ProteinsEbola VaccinesImmunoglobulin GRecombinant Fusion ProteinsViral Envelope Proteins

Identifiers

PMID32513849
PMCPMC7343599
OpenAlexW3033753736

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.