Evidence map›Paper›PMID 32513815›Full record

ArticleGenetics2020

Estimation of the Genome-Wide Mutation Rate and Spectrum in the Archaeal Species

Sibel Kucukyildirim, Megan Behringer, Emily M Williams, Thomas G Doak, Michael Lynch

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. A Single Nucleotide Change in theApplied and environmental microbiology · 2022
    Article
  6. Article
  7. Article
  8. Open biology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Sibel KucukyildirimDepartment of Biology, Indiana University, Bloomington 47405, Indiana sibelkucukyildirim@gmail.com.ORCID 0000-0003-2241-3060
Megan BehringerDepartment of Biology, Indiana University, Bloomington 47405, Indiana.ORCID 0000-0001-7036-6014
Emily M WilliamsDepartment of Biology, Indiana University, Bloomington 47405, Indiana.
Thomas G DoakDepartment of Biology, Indiana University, Bloomington 47405, Indiana.ORCID 0000-0001-5487-553X
Michael LynchDepartment of Biology, Indiana University, Bloomington 47405, Indiana.
Indiana University Bloomington · US

Funding

Causes and Population-genetic Consequences of Molecular VariationR35GM122566 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI Michael R LYNCH · 2017 to 2026
$7.7M
The Rate and Molecular Spectrum of Spontaneous MutationsR01GM036827 · NIGMS · UNIVERSITY OF OREGON · PI LYNCH, MICHAEL R · 1988 to 2016
$5.7M
Genetic and Environmental Determinants of Population Structure During Escherichia coli Experimental Evolution.F32GM123703 · NIGMS · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI BEHRINGER, MEGAN GRACE · 2017 to 2018
$118k
NIGMS NIH HHS F32 GM123703NIGMS NIH HHS R01 GM036827NIGMS NIH HHS R35 GM122566
6 · The paper itself

Abstract

Organisms adapted to life in extreme habitats (extremophiles) can further our understanding of the mechanisms of genetic stability, particularly replication and repair. Despite the harsh environmental conditions they endure, these extremophiles represent a great deal of the Earth's biodiversity. Here, for the first time in a member of the archaeal domain, we report a genome-wide assay of spontaneous mutations in the halophilic species

Indexed as

DNA ReplicationGenomeMutationMutation RateArchaeal ProteinsHaloferax volcaniiPhylogenyArchaeal ProteinsAT biasgenome copy numberHaloferax volcaniimutation accumulationmutation ratemutation spectrum

Identifiers

PMID32513815
PMCPMC7404244
OpenAlexW3033018015

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.