Evidence map›Paper›PMID 32513800›Full record

ArticleAntimicrobial agents and chemotherapy2020

Inhibition of Fatty Acid Oxidation as a New Target To Treat Primary Amoebic Meningoencephalitis.

Maarten J Sarink, Aloysius G M Tielens, Annelies Verbon, Robert Sutak, Jaap J van Hellemond

Open access · hybridAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Differential Growth Rates andMicrobiology spectrum · 2022
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Maarten J SarinkDepartment of Medical Microbiology and Infectious Diseases, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands.
Aloysius G M TielensDepartment of Medical Microbiology and Infectious Diseases, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands.
Annelies VerbonDepartment of Medical Microbiology and Infectious Diseases, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands.
Robert SutakDepartment of Parasitology, Faculty of Science, Charles University, BIOCEV, Vestec, Czech Republic.
Jaap J van HellemondDepartment of Medical Microbiology and Infectious Diseases, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands j.vanhellemond@erasmusmc.nl.ORCID 0000-0003-4862-7796
Erasmus MC · NLCharles University · CZUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary amoebic meningoencephalitis (PAM) is a rapidly fatal infection caused by the free-living amoeba

Indexed as

Central Nervous System Protozoal InfectionsMeningoencephalitisNaegleriaNaegleria fowleriAmphotericin BAnimalsFatty AcidsAmphotericin BFatty Acidsdrug targetsenergy metabolismlipid metabolismNaegleria fowleriNaegleria gruberitherapythioridazinetreatment

Identifiers

PMID32513800
PMCPMC7526813
OpenAlexW3033826417

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.