Evidence map›Paper›PMID 32513714›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Coupling of Ca

Yanyan Geng, Zengqin Deng, Guohui Zhang, Gonzalo Budelli, Alice Butler, Peng Yuan, Jianmin Cui, Lawrence Salkoff, Karl L Magleby

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Fifty years of gating currents and channel gating.The Journal of general physiology · 2023
    Review
  6. SLO3: A Conserved Regulator of Sperm Membrane Potential.International journal of molecular sciences · 2023
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Regulatory mechanisms of mitochondrial BKChannels (Austin, Tex.) · 2021
    Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yanyan GengDepartment of Physiology and Biophysics, University of Miami Miller School of Medicine, Miami FL 33136.
Zengqin DengDepartment of Cell Biology and Physiology, Washington University, St. Louis, MO 63110.ORCID 0000-0002-5658-2068
Guohui ZhangDepartment of Biomedical Engineering, Washington University, St. Louis, MO 63110.ORCID 0000-0001-6905-0637
Gonzalo BudelliDepartment of Neuroscience, Washington University, St. Louis, MO 63110.
Alice ButlerDepartment of Neuroscience, Washington University, St. Louis, MO 63110.ORCID 0000-0002-9079-7812
Peng YuanDepartment of Cell Biology and Physiology, Washington University, St. Louis, MO 63110.ORCID 0000-0002-5660-225X
Jianmin CuiDepartment of Biomedical Engineering, Washington University, St. Louis, MO 63110.ORCID 0000-0002-9198-6332
Lawrence SalkoffDepartment of Neuroscience, Washington University, St. Louis, MO 63110.ORCID 0000-0001-7400-6550
Karl L MaglebyDepartment of Physiology and Biophysics, University of Miami Miller School of Medicine, Miami FL 33136; kmagleby@miami.edu.
Washington University in St. Louis · USUniversity of Miami · US

Funding

Mechanism of BK Channel GatingR01HL142301 · NHLBI · WASHINGTON UNIVERSITY · PI SILVA, JONATHAN R · 2018 to 2021
$2.9M
Testing a Novel Push-Pull Mechanism for Ca2+-Dependent Coupling in BK ChannelsR01GM114694 · NIGMS · WASHINGTON UNIVERSITY · PI MAGLEBY, KARL L, SALKOFF, LAWRENCE B · 2016 to 2019
$1.9M
NHLBI NIH HHS R01 HL142301NIGMS NIH HHS R01 GM114694
6 · The paper itself

Abstract

Large-conductance Ca

Indexed as

Allosteric RegulationAnimalsCalciumCations, DivalentCell MembraneCrystallography, X-RayIon Channel GatingLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitsMembrane PotentialsMutagenesis, Site-DirectedOocytesPatch-Clamp TechniquesProlineProtein Conformation, alpha-HelicalProtein DomainsStructure-Activity RelationshipCalciumCations, DivalentKCNMA1 protein, humanKcnma1 protein, mouseLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitsProlineallosteric couplingBK channelCa2+-activated K+ channelpatch clampSlo1 channel

Identifiers

PMID32513714
PMCPMC7321994
OpenAlexW3033178544

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.