Evidence map›Paper›PMID 32513699›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Spatial confinement of receptor activity by tyrosine phosphatase during directional cell migration.

Zhiwen Zhu, Yongping Chai, Huifang Hu, Wei Li, Wen-Jun Li, Meng-Qiu Dong, Jia-Wei Wu, Zhi-Xin Wang, Guangshuo Ou

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Single-cell transcriptomic profiling ofbioRxiv : the preprint server for biology · 2025
    Article
  3. Article
  4. Transcripts from themicroPublication biology · 2025
    Article
  5. Article
  6. Actin filament debranching regulates cell polarity during cell migration and asymmetric cell division.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Zhiwen ZhuTsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing 100084, China.
Yongping ChaiTsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing 100084, China.
Huifang HuSchool of Life Sciences, Tsinghua University, Beijing 100084, China.
Wei LiSchool of Medicine, Tsinghua University, Beijing 100084, China.ORCID 0000-0001-9133-461X
Wen-Jun LiNational Institute of Biological Science, Beijing 102206, China.ORCID 0000-0003-4204-5621
Meng-Qiu DongNational Institute of Biological Science, Beijing 102206, China.ORCID 0000-0002-6094-1182
Jia-Wei WuSchool of Life Sciences, Tsinghua University, Beijing 100084, China.
Zhi-Xin WangSchool of Life Sciences, Tsinghua University, Beijing 100084, China.
Guangshuo OuTsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing 100084, China; guangshuoou@mail.tsinghua.edu.cn.
National Institute of Biological Sciences, Beijing · CNTsinghua University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Directional cell migration involves signaling cascades that stimulate actin assembly at the leading edge, and additional pathways must inhibit actin polymerization at the rear. During neuroblast migration in

Indexed as

Actin CytoskeletonActin-Related Protein 2-3 ComplexActinsAnimalsAnimals, Genetically ModifiedCaenorhabditis elegansCaenorhabditis elegans ProteinsCell MovementCell PolarityLow Density Lipoprotein Receptor-Related Protein-1Membrane ProteinsNeuronsPhosphorylationProtein KinasesProtein Tyrosine PhosphatasesSignal TransductionActin-Related Protein 2-3 ComplexActinsCaenorhabditis elegans ProteinsLow Density Lipoprotein Receptor-Related Protein-1Membrane ProteinsMIG-13 protein, Caenorhabditis elegansProtein KinasesProtein Tyrosine PhosphatasesPTP-3 protein, C elegansSRC-1 protein, C eleganscell polaritycytoskeletondirectional cell migrationtyrosine kinase and phosphatase

Identifiers

PMID32513699
PMCPMC7321996
OpenAlexW3032958766

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.