Evidence map›Paper›PMID 32513690›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

A long noncoding RNA regulates inflammation resolution by mouse macrophages through fatty acid oxidation activation.

Yukiteru Nakayama, Katsuhito Fujiu, Ryuzaburo Yuki, Yumiko Oishi, Masaki Suimye Morioka, Takayuki Isagawa, Jun Matsuda, Tsukasa Oshima, Takumi Matsubara, Junichi Sugita and 7 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 51 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. iScience · 2026
    Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Palmitic Acid-Induced Long Noncoding RNAArteriosclerosis, thrombosis, and vascular biology · 2023
    Article
  17. A New "Lnc" to Brake Inflammation.Arteriosclerosis, thrombosis, and vascular biology · 2023
    Article
  18. Review
  19. A proinflammatory long noncoding RNA Lncenc1 regulates inflammasome activation in macrophage.American journal of physiology. Lung cellular and molecular physiology · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 1 country.

Yukiteru NakayamaDepartment of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo, Bunkyo-ku, 113-8654 Tokyo, Japan.ORCID 0000-0002-4694-8660
Katsuhito FujiuDepartment of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo, Bunkyo-ku, 113-8654 Tokyo, Japan.
Ryuzaburo YukiDepartment of Disease Biology and Molecular Medicine, Graduate School of Medicine, Chiba University, Chuo-Ku, 260-8670 Chiba, Japan.ORCID 0000-0002-4072-3559
Yumiko OishiDepartment of Biochemistry & Molecular Biology, Nippon Medical School, Bunkyo-ku, 113-8602 Tokyo, Japan.ORCID 0000-0002-4761-0952
Masaki Suimye MoriokaDepartment of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo, Bunkyo-ku, 113-8654 Tokyo, Japan.ORCID 0000-0003-3511-7279
Takayuki IsagawaData Science Center, Jichi Medical University, Shimotsuke-shi, 392-0498 Tochigi, Japan.
Jun MatsudaDepartment of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo, Bunkyo-ku, 113-8654 Tokyo, Japan.
Tsukasa OshimaDepartment of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo, Bunkyo-ku, 113-8654 Tokyo, Japan.
Takumi MatsubaraDepartment of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo, Bunkyo-ku, 113-8654 Tokyo, Japan.ORCID 0000-0002-8946-2695
Junichi SugitaDepartment of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo, Bunkyo-ku, 113-8654 Tokyo, Japan.
Fujimi KudoDepartment of Disease Biology and Molecular Medicine, Graduate School of Medicine, Chiba University, Chuo-Ku, 260-8670 Chiba, Japan.
Atsushi KanedaDepartment of Molecular Oncology, Graduate School of Medicine, Chiba University, Chuo-ku, 260-8670 Chiba, Japan.ORCID 0000-0002-6980-5515
Yusuke EndoDepartment of Immunology, Graduate School of Medicine, Chiba University and AMED-CREST, AMED, Chuo-ku, 260-8670 Chiba, Japan.
Toshinori NakayamaDepartment of Immunology, Graduate School of Medicine, Chiba University and AMED-CREST, AMED, Chuo-ku, 260-8670 Chiba, Japan.ORCID 0000-0002-1434-2007
Ryozo NagaiJichi Medical University, Shimotsuke-shi, 392-0498 Tochigi, Japan.
Issei KomuroDepartment of Cardiovascular Medicine, Graduate School of Medicine, University of Tokyo, Bunkyo-ku, 113-8654 Tokyo, Japan.
Ichiro ManabeDepartment of Disease Biology and Molecular Medicine, Graduate School of Medicine, Chiba University, Chuo-Ku, 260-8670 Chiba, Japan; manabe-tky@umin.ac.jp.ORCID 0000-0001-9481-6673
The University of Tokyo · JPChiba University · JPJichi Medical University · JPNippon Medical School · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proper resolution of inflammation is vital for repair and restoration of homeostasis after tissue damage, and its dysregulation underlies various noncommunicable diseases, such as cardiovascular and metabolic diseases. Macrophages play diverse roles throughout initial inflammation, its resolution, and tissue repair. Differential metabolic reprogramming is reportedly required for induction and support of the various macrophage activation states. Here we show that a long noncoding RNA (lncRNA),

Indexed as

AnimalsDisease Models, AnimalFatty AcidsGene Knockdown TechniquesHumansInflammationLipopolysaccharidesMacrophage ActivationMacrophagesMaleMiceMitochondrial Trifunctional Protein, beta SubunitOxidation-ReductionPrimary Cell CultureRNA, Long NoncodingSkinFatty AcidsHadhb protein, mouseLipopolysaccharidesMitochondrial Trifunctional Protein, beta SubunitRNA, Long NoncodinginflammationLong noncoding RNAmacrophage

Identifiers

PMID32513690
PMCPMC7322040
OpenAlexW3033313447

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.