Evidence map›Paper›PMID 32513619›Full record

ArticleTrends in immunology2020

Where There's Smoke, There's Fire: Inflammation Drives MDS.

Gandhar K Datar, Margaret A Goodell

Abstract readComment
PubMed Publisher
In one paragraph

Article in Trends in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. What Exactly Is Inflammation (and What Is It Not?).International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Gandhar K DatarCancer and Cell Biology Graduate Program, Baylor College of Medicine, Houston, TX 77008, USA; Department of Molecular and Cellular Biology, Center for Cell and Gene Therapy, and Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX 77008, USA.
Margaret A GoodellCancer and Cell Biology Graduate Program, Baylor College of Medicine, Houston, TX 77008, USA; Department of Molecular and Cellular Biology, Center for Cell and Gene Therapy, and Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX 77008, USA. Electronic address: goodell@bcm.edu.
Baylor College of Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic inflammation has been implicated in myelodysplastic syndrome (MDS); however, its role in disease progression is unclear. In a new study by Muto et al., MDS stem cells sparked with TRAF6-activated innate immune signaling were found to outcompete normal counterparts only when fueled by environmental inflammatory stimuli. Non-canonical NF-κB signaling is implicated in inflammatory synergy and MDS progression.

Indexed as

FiresMyelodysplastic SyndromesHumansInflammationMyelopoiesisSmokeSmoke

Identifiers

PMID32513619
OpenAlexW3034018455

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.