Evidence map›Paper›PMID 32513597›Full record

ReviewSeminars in fetal & neonatal medicine2020

Prevention of preeclampsia.

Marwan Ma'ayeh, Maged M Costantine

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in fetal & neonatal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed, 2 pooled it
4.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed, 2 syntheses or guidelines pooled it, 146 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Therapeutic Interventions for Preeclampsia: Integrating Placental and Maternal Perspectives.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026
    Review
  6. Genetic Correlation and Causal Inference Between Female Fat Distribution and Preeclampsia: An Integrative Genomic Study.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  7. International journal of molecular sciences · 2026
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Deletion of endothelial KLF4 as a model for preeclampsia.bioRxiv : the preprint server for biology · 2026
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Unveiling preeclampsia: diagnostic value and potential molecular mechanisms of abnormally methylated immune-related genes.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2026
    Article
  20. Article

22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Marwan Ma'ayehDepartment of Obstetrics & Gynecology, The Ohio State University College of Medicine, 395 W 12th Ave, 5th Floor, Columbus, OH, USA. Electronic address: maay01@osumc.edu.
Maged M CostantineDepartment of Obstetrics & Gynecology, The Ohio State University College of Medicine, 395 W 12th Ave, 5th Floor, Columbus, OH, USA.
The Ohio State University · US

Funding

NICHD Maternal Fetal Medicine Units NetworkUG1HD027915 · NICHD · OHIO STATE UNIVERSITY · PI Maged Costantine · 2016 to 2026
$3.3M
1/2 A randomized controlled trial of pravastatin to prevent preeclampsia in high-risk womenUH3HL140131 · NHLBI · UNIVERSITY OF TEXAS MED BR GALVESTON · PI COSTANTINE, MAGED · 2019 to 2023
$366k
NHLBI NIH HHS UH3 HL140131NICHD NIH HHS UG1 HD027915
6 · The paper itself

Abstract

Preeclampsia is an obstetric disorder that affects 3-8% of pregnant women and remains a leading cause of short- and long-term neonatal and maternal morbidity and mortality. Professional societies recommend the use of low dose aspirin to prevent preeclampsia in high-risk women. However, interest in prevention of this disease and better understanding of its pathophysiology have led to growing research on other agents. This review focuses on the main therapeutic agents evaluated or in use for preeclampsia prevention.

Indexed as

AspirinFemaleFibrinolytic AgentsHumansHypertensionPre-EclampsiaPregnancyAspirinFibrinolytic AgentsAspirinEsomeprazoleMetforminPreeclampsiaPregnancyStatin

Identifiers

PMID32513597
PMCPMC8236336
OpenAlexW3033297444

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.