Evidence map›Paper›PMID 32513248›Full record

ArticleParasites & vectors2020

Insecticide resistance, fitness and susceptibility to Zika infection of an interbred Aedes aegypti population from Rio de Janeiro, Brazil.

Carlucio Rocha Dos Santos, Cynara de Melo Rodovalho, Willy Jablonka, Ademir Jesus Martins, José Bento Pereira Lima, Luciana Dos Santos Dias, Mário Alberto Cardoso da Silva Neto, Georgia Correa Atella

Abstract read
In one paragraph

Article in Parasites & vectors, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Detection of Dengue Virus inMicroorganisms · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Molecules (Basel, Switzerland) · 2025
    Article
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  11. Article
  12. Review
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Carlucio Rocha Dos SantosLaboratório de Sinalização Celular Programa de Biologia Molecular e Biotecnologia, Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil. carluciorsantos@gmail.com.
Cynara de Melo RodovalhoLaboratório de Fisiologia e Controle de Artrópodes Vetores, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, RJ, Brazil.
Willy JablonkaLaboratório de Sinalização Celular Programa de Biologia Molecular e Biotecnologia, Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Ademir Jesus MartinsLaboratório de Fisiologia e Controle de Artrópodes Vetores, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, RJ, Brazil.
José Bento Pereira LimaLaboratório de Fisiologia e Controle de Artrópodes Vetores, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, RJ, Brazil.
Luciana Dos Santos DiasLaboratório de Fisiologia e Controle de Artrópodes Vetores, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, RJ, Brazil.
Mário Alberto Cardoso da Silva NetoLaboratório de Sinalização Celular Programa de Biologia Molecular e Biotecnologia, Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Georgia Correa AtellaLaboratório de Bioquímica de Lipídios e Lipoproteínas, Programa de Biologia Molecular e Biotecnologia, Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.

Funding

Genetic Studies of Dengue Vectors in BrazilU01AI115595 · NIAID · YALE UNIVERSITY · PI POWELL, JEFFREY R · 2015 to 2019
$3.6M
STUDIES OF RETINITIS PIGMENTOSA AND ALLIED DISEASESU01EY002014 · NEI · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI BERSON, ELIOT L · 1988 to 1989
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STUDIES OF RETINITIS PIGMENTOSA AND ALLIED DISEASESU10EY002014 · NEI · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI BERSON, ELIOT L · 1990 to 1993
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Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro - Faperj 210.896/2014NIAID NIH HHS U01 AI115595
6 · The paper itself

Abstract

backgroundAedes aegypti is a vector of high relevance, since it transmits several arboviruses, including dengue, chikungunya and Zika. Studies on vector biology are usually conducted with laboratory strains presenting a divergent genetic composition from field populations. This may impair vector control policies that were based on laboratory observations employing only long maintained laboratory strains. In the present study we characterized a laboratory strain interbreed with Ae. aegypti collected from five different localities in Rio de Janeiro (Aedes Rio), for insecticide resistance (IR), IR mechanisms, fitness and Zika virus infection.

methodsWe compared the recently established Aedes Rio with the laboratory reference strain Rockefeller. Insecticide resistance (deltamethrin, malathion and temephos), activity of metabolic resistance enzymes and kdr mutation frequency were determined. Some life table parameters (longevity, blood-feeding, number and egg viability) and Zika virus susceptibility was also determined.

resultsAedes Rio showed resistance to deltamethrin (resistance ratio, RR

conclusionSelected conditions in the field, such as IR mechanisms, may result in pleiotropic effects that interfere in general physiology of the insect. Therefore, it is important to well characterize field populations to be tested in parallel with laboratory reference strains. This practice would improve the significance of laboratory tests for vector control methods.

Indexed as

Genetic FitnessInsecticidesAedesAnimalsBiological AssayBrazilBreedingDisease SusceptibilityFemaleGenotypeInsecticide ResistanceMaleMosquito VectorsInsecticidesAedes aegyptiFitnessInsecticide resistanceMosquito

Identifiers

PMID32513248
PMCPMC7281914

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.