Evidence map›Paper›PMID 32513192›Full record

Trial reportAIDS research and therapy2020

Habit formation in support of antiretroviral medication adherence in clinic-enrolled HIV-infected adults: a qualitative assessment using free-listing and unstructured interviewing in Kampala, Uganda.

Larissa Jennings Mayo-Wilson, Bianca Devoto, Jessica Coleman, Barbara Mukasa, Angela Shelton, Sarah MacCarthy, Uzaib Saya, Harriet Chemusto, Sebastian Linnemayr

3 registry-linked trialsOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in AIDS research and therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03494777 nacompletednot on this map

Behavioral Economics Incentives to Support HIV Treatment Adherence in Sub-Saharan Africa

TypeinterventionalSponsorRANDRan2018 to 2023Enrolled331ConditionsHIV/AIDSArmsIncentivization based on high adherence, Incentivization based on timely clinic visit, Annual adherence prize drawing, Annual viral suppression-based prize drawing, Year 2 booster
NCT05131165 nacompletednot on this mapstarted 2021, after this paper: background citation

INcentives and ReMINDers to Improve Long-term Medication Adherence

TypeinterventionalSponsorRANDRan2021 to 2023Enrolled166ConditionsHIV/AIDSArmsDaily Text Messages, Incentivization based on timely ART adherence
NCT06949774 narecruitingnot on this mapstarted 2025, after this paper: background citation

INcentives and ReMINDers to Improve Long-term Medication Adherence

TypeinterventionalSponsorRANDRan2025 to 2029Enrolled550ConditionsHIV/AIDS, Medication Adherence, HabitsArmsDaily Text Messages, Incentivization based on timely ART adherence
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Larissa Jennings Mayo-WilsonIndiana University School of Public Health, Department of Applied Health Science, Center for Sexual Health Promotion, 1025 E. 7th Street, Bloomington, IN, USA. ljmayowi@iu.edu.
Bianca DevotoJohns Hopkins Bloomberg School of Public Health, Department of International Health, Social and Behavioral Interventions Program, 615 N. Wolfe Street, Baltimore, MD, USA.
Jessica ColemanJohns Hopkins Bloomberg School of Public Health, Department of International Health, Social and Behavioral Interventions Program, 615 N. Wolfe Street, Baltimore, MD, USA.
Barbara MukasaMildmay Uganda, Mildmay Hospital and Institute of Health Sciences, Box 24985, Kampala, Uganda.
Angela SheltonJohns Hopkins Bloomberg School of Public Health, Department of International Health, Social and Behavioral Interventions Program, 615 N. Wolfe Street, Baltimore, MD, USA.
Sarah MacCarthyRAND Corporation, 1776 Main Street, Santa Monica, CA, USA.
Uzaib SayaRAND Corporation, 1776 Main Street, Santa Monica, CA, USA.
Harriet ChemustoMildmay Uganda, Mildmay Hospital and Institute of Health Sciences, Box 24985, Kampala, Uganda.
Sebastian LinnemayrRAND Corporation, 1776 Main Street, Santa Monica, CA, USA.
Johns Hopkins University · USRAND Corporation · USMildmay Uganda · UGIndiana University Bloomington · US

Funding

Behavioral Economics Incentives to Support HIV Treatment Adherence in Sub-Saharan AfricaR01MH110350 · NIMH · RAND CORPORATION · PI LINNEMAYR, SEBASTIAN · 2017 to 2021
$2.8M
NIMH NIH HHS R01 MH110350NIMH NIH HHS R01MH110350
6 · The paper itself

Abstract

backgroundDespite initial high motivation, individuals receiving antiretroviral therapy (ART) for several years may experience incomplete adherence over time, increasing their risk of HIV-related morbidity and mortality. Habits, defined as automatic and regular practices, do not rely on conscious effort, and may therefore support high long-term ART adherence.

methodsThis qualitative study contributes to the evidence on how clients with adherence problems remember and form habits to take ART medications. Free-listing and unstructured interviewing were used among 42 clinic-enrolled adults in Kampala, Uganda who were receiving ART and participating in a randomized clinical trial for treatment adherence (clinicaltrials.gov: NCT03494777). Data were coded and analyzed using inductive content analysis.

resultsFindings indicated that clients' most routine habits (eating, bathing, sleeping) did not always occur at the same time or place, making it difficult to reliably link to pill-taking times. Efforts to improve ART habits included having a relative to ask about pill-taking, re-packaging medications, leaving medications in view, using alarms, carrying water, or linking pill-taking to radio/prayer schedules. Reported challenges were adhering to ART schedules during changing employment hours, social activities, and travel.

conclusionWhile habit-forming interventions have the potential to improve ART adherence, targeting treatment-mature clients' existing routines may be crucial in this population.

Indexed as

Drug MonitoringHabitsAdultAmbulatory Care FacilitiesAnti-Retroviral AgentsFemaleHIV InfectionsHumansMaleMedication AdherenceMiddle AgedQualitative ResearchSocial SupportUgandaYoung AdultAnti-Retroviral AgentsAdherenceAntiretroviral therapyARTHabit formationHIVQualitativeUganda

Identifiers

PMID32513192
PMCPMC7278190
OpenAlexW3033412291

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.