SynthesisJournal of translational medicine2020
The clinical application of electrical impedance technology in the detection of malignant neoplasms: a systematic review.
Synthesis in Journal of translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Surgical identification of brain tumour margins through impedance monitoring and electrocorticography and the potential for their combined use: A systematic review.Neurosurgical review · 2024Pooled it
- Applications of bioimpedance measurement in clinical and allied fields: a comprehensive review.Biomedical engineering online · 2026Review
- Bioimpedance Spectroscopy as a Triage-Support Tool for Breast Cancer Prioritization in a Low- and Middle-Income Country: A Commentary on Published Evidence From a Bioimpedance-Based Device.Breast cancer : basic and clinical research · 2026Article
- Bioimpedance in neurosurgery for tumor margin delineation.Brain & spine · 2026Article
- Electrical impedance tomography: from technical innovations to bedside clinical solutions.World journal of emergency medicine · 2025Article
- A Clinically Feasible Electrode Array for 3D Intraoperative Electrical Impedance Tomography-Based Surgical Margin Assessment in Robot-Assisted Radical Prostatectomy.IEEE transactions on bio-medical engineering · 2024Article
- Electrical Tumor Detection Probe Calibrated to Diagnose Gastrointestinal Cancer Mass in Real-Time.Journal of clinical medicine · 2024Article
- Review
- Detection of High-Grade Cervical Intraepithelial Neoplasia by Electrical Impedance Spectroscopy in Women Diagnosed with Low-Grade Cervical Intraepithelial Neoplasia in Cytology.Life (Basel, Switzerland) · 2023Article
- Tissue-Engineered Cochlear Fibrosis Model Links Complex Impedance to Fibrosis Formation for Cochlear Implant Patients.Advanced healthcare materials · 2023Article
- Electrical Impedance Tomography: From the Traditional Design to the Novel Frontier of Wearables.Sensors (Basel, Switzerland) · 2023Review
- Electrical Impedance Analysis for Lung Cancer: A Prospective, Multicenter, Blind Validation Study.Frontiers in oncology · 2022Article
- Tissue Characterization Using an Electrical Bioimpedance Spectroscopy-Based Multi-Electrode Probe to Screen for Cervical Intraepithelial Neoplasia.Diagnostics (Basel, Switzerland) · 2021Article
- [Organoids for the advancement of intraoperative diagnostic procedures].Der Urologe. Ausg. A · 2021Review
- Correlation between electrical characteristics and biomarkers in breast cancer cells.Scientific reports · 2021Article
- Portable Electrical Impedance Prescreening for Breast tissue suspicious for malignancy: Model Optimization and Clinical Performance of the Julieta Device in a Multicenter Cross-Sectional Study in Colombia.Technology in cancer research & treatmentObservational
- Bioimpedance: A Tool for Screening Oral Cancer - A Systematic Review.Contemporary clinical dentistryReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundElectrical impedance technology has been well established for the last 20 years. Recently research has begun to emerge into its potential uses in the detection and diagnosis of pre-malignant and malignant conditions. The aim of this study was to systematically review the clinical application of electrical impedance technology in the detection of malignant neoplasms.
methodsA search of Embase Classic, Embase and Medline databases was conducted from 1980 to 22/02/2018 to identify studies reporting on the use of bioimpedance technology in the detection of pre-malignant and malignant conditions. The ability to distinguish between tissue types was defined as the primary endpoint, and other points of interest were also reported.
results731 articles were identified, of which 51 reported sufficient data for analysis. These studies covered 16 different cancer subtypes in a total of 7035 patients. As the studies took various formats, a qualitative analysis of each cancer subtype's data was undertaken. All the studies were able to show differences in electrical impedance and/or related metrics between malignant and normal tissue.
conclusionsElectrical impedance technology provides a novel method for the detection of malignant tissue, with large studies of cervical, prostate, skin and breast cancers showing encouraging results. Whilst these studies provide promising insights into the potential of this technology as an adjunct in screening, diagnosis and intra-operative margin assessment, customised development as well as multi-centre clinical trials need to be conducted before it can be reliably employed in the clinical detection of malignant tissue.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.