Evidence map›Paper›PMID 32512881›Full record

ArticleCancers2020

Potential Onco-Suppressive Role of miR122 and miR144 in Uveal Melanoma through ADAM10 and C-Met Inhibition.

Adriana Amaro, Michela Croce, Silvano Ferrini, Gaia Barisione, Marina Gualco, Patrizia Perri, Ulrich Pfeffer, Martine J Jager, Sarah E Coupland, Carlo Mosci and 4 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Gene therapy for uveal melanoma.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  2. Article
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  5. Article
  6. Article
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  9. Emerging roles of microRNAs and their implications in uveal melanoma.Cellular and molecular life sciences : CMLS · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 3 countries.

Adriana AmaroIRCCS Ospedale Policlinico San Martino, 16132 Genova, Italy.ORCID 0000-0002-1573-7756
Michela CroceIRCCS Ospedale Policlinico San Martino, 16132 Genova, Italy.ORCID 0000-0003-4683-4951
Silvano FerriniIRCCS Ospedale Policlinico San Martino, 16132 Genova, Italy.
Gaia BarisioneIRCCS Ospedale Policlinico San Martino, 16132 Genova, Italy.
Marina GualcoAzienda Sociosanitaria Ligure 3 (ASL3), Sistema Sanitario Regionale Liguria, 16149 Genova, Italy.
Patrizia PerriIstituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Istituto G. Gaslini|Ospedale Pediatrico Gaslini, 16147 Genova, Italy.ORCID 0000-0003-2538-8278
Ulrich PfefferIRCCS Ospedale Policlinico San Martino, 16132 Genova, Italy.ORCID 0000-0003-0872-4671
Martine J JagerLeiden University Medical Center, 2333ZA Leiden, The Netherlands.ORCID 0000-0003-2261-3820
Sarah E CouplandDepartment of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool L7 8TX, UK.ORCID 0000-0002-1464-2069
Carlo MosciGalliera Hospital, 16128 Genova, Italy.
Gilberto FilaciIRCCS Ospedale Policlinico San Martino, 16132 Genova, Italy.
Marina FabbiIRCCS Ospedale Policlinico San Martino, 16132 Genova, Italy.ORCID 0000-0002-4203-2022
Paola QueiroloIEO Institute of Oncology Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), 20141 Milan, Italy.
Rosaria GangemiIRCCS Ospedale Policlinico San Martino, 16132 Genova, Italy.
Ospedale Policlinico San Martino · ITEnte Ospedaliero Ospedali Galliera · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITIstituto Giannina Gaslini · ITLeiden University Medical Center · NLUniversity of Liverpool · GB

Funding

Associazione Italiana per la Ricerca sul Cancro AIRC, IG 17103).Compagnia di San Paolo Prot. : 2017.AAI4504.U5092
6 · The paper itself

Abstract

Uveal melanoma (UM) is a rare tumor of the eye that leads to deadly metastases in about half of the patients. ADAM10 correlates with c-Met expression in UM and high levels of both molecules are related to the development of metastases. MiR122 and miR144 modulate

Indexed as

ADAM10c-MetmiRNAonco-suppressoruveal melanoma

Identifiers

PMID32512881
PMCPMC7352235
OpenAlexW3034013823

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.