Evidence map›Paper›PMID 32512697›Full record

ReviewInternational journal of molecular sciences2020

Gastric Cancer: Epidemiology, Risk Factors, Classification, Genomic Characteristics and Treatment Strategies.

Julita Machlowska, Jacek Baj, Monika Sitarz, Ryszard Maciejewski, Robert Sitarz

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 857 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
857citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

857 citing papers in PubMed, 10 syntheses or guidelines pooled it.

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  18. Germline whole-exome sequencing identifies CTNND1 as a candidate gene for hereditary gastric cancer in a large Brazilian cohort.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026
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797 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Julita MachlowskaCenter for Medical Genomics OMICRON, Jagiellonian University Medical College, 31-034 Kraków, Poland.ORCID 0000-0001-9951-9248
Jacek BajDepartment of Human Anatomy, Medical University of Lublin, 20-090 Lublin, Poland.ORCID 0000-0002-1372-8987
Monika SitarzDepartment of Conservative Dentistry with Endodontics, Medical University of Lublin, 20-090 Lublin, Poland.
Ryszard MaciejewskiDepartment of Human Anatomy, Medical University of Lublin, 20-090 Lublin, Poland.
Robert SitarzDepartment of Human Anatomy, Medical University of Lublin, 20-090 Lublin, Poland.ORCID 0000-0001-7267-9516

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer (GC) is one of the most common malignancies worldwide and it is the fourth leading cause of cancer-related death. GC is a multifactorial disease, where both environmental and genetic factors can have an impact on its occurrence and development. The incidence rate of GC rises progressively with age; the median age at diagnosis is 70 years. However, approximately 10% of gastric carcinomas are detected at the age of 45 or younger. Early-onset gastric cancer is a good model to study genetic alterations related to the carcinogenesis process, as young patients are less exposed to environmental carcinogens. Carcinogenesis is a multistage disease process specified by the progressive development of mutations and epigenetic alterations in the expression of various genes, which are responsible for the occurrence of the disease.

Indexed as

AnimalsCell Transformation, NeoplasticCombined Modality TherapyDisease ManagementDisease SusceptibilityGenomicsHumansIncidenceMolecular Diagnostic TechniquesPatient Outcome AssessmentPopulation SurveillanceRisk AssessmentRisk FactorsStomach Neoplasmsadjuvant chemotherapygastric cancerH. pyloriincidencemolecular markersmortalitytargeted therapy

Identifiers

PMID32512697
PMCPMC7312039

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.