ArticleAmerican journal of ophthalmology2020
Understanding the Impact of Residual Amblyopia on Functional Vision and Eye-related Quality of Life Using the PedEyeQ.
Article in American journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07226141 (Valproate for the Treatment of Residual Amblyopia), which is not on this map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Valproate for the Treatment of Residual Amblyopia
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Interventions for improving adherence to amblyopia treatments in children.The Cochrane database of systematic reviews · 2025Pooled it
- Research hotspots and trends of amblyopia treatment from 2015 to 2025: a bibliometric analysis.Frontiers in neuroscience · 2025Pooled it
- Amblyopia and strabismus: Psychosocial characteristics - results from the Gutenberg Health Study (GHS).Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Barriers and opportunities in pediatric ophthalmology: a cross-sectional survey among Brazilian ophthalmologists.Scientific reports · 2026Article
- Visually Guided Saccades in Amblyopia and Strabismus: The Roles of Sensory Deficits and Nystagmus.Investigative ophthalmology & visual science · 2026Article
- Vision screening of Greenlandic children evaluating efficacy, coverage and future directions.Acta ophthalmologica · 2026Article
- Vision screening and refraction of Greenlandic schoolchildren.Acta ophthalmologica · 2025Article
- Childhood amblyopia in a tertiary eye care center in western India.International journal of ophthalmology · 2025Article
- Article
- Qualitative Exploration of the Visual Function Impairments and Health-Related Quality of Life Impacts of Amblyopia in Adult and Pediatric Populations.Ophthalmology and therapy · 2023Article
- Stereoptic serious games as a visual rehabilitation tool for individuals with a residual amblyopia (AMBER trial): a protocol for a crossover randomized controlled trial.BMC ophthalmology · 2023Article
- Translating and evaluating the Chinese version of Pediatric Eye Questionnaire (PedEyeQ-CN) for children.Eye (London, England) · 2023Article
- Amblyopia and the whole child.Progress in retinal and eye research · 2023Review
- Comparison of Functional Vision and Eye-Related Quality of Life between Myopic Children Treated with Orthokeratology and Single-Vision Spectacles in Southern China.Journal of ophthalmology · 2023Article
- Effect of Viewing Conditions on Fixation Eye Movements and Eye Alignment in Amblyopia.Investigative ophthalmology & visual science · 2022Article
- A Retrospective Study on the Eye-Related Quality of Life, Functional Vision, and Their Determinants Among Children Following Congenital and Developmental Cataracts Surgery and Its Impact on Their Families Using the PedEyeQ.Frontiers in public health · 2022Article
- Using a Computerised Staircase and Incremental Optotype Sizes to Improve Visual Acuity Assessment Accuracy.The British and Irish orthoptic journal · 2022Article
- A randomized study of network-based perception learning in the treatment of amblyopia children.International journal of ophthalmology · 2022Article
- Recent Advances in Screening and Treatment for Amblyopia.Ophthalmology and therapy · 2021Review
- Quality of life and functional vision across pediatric eye conditions assessed using the PedEyeQ.Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
purposeTo evaluate the effect of residual amblyopia on functional vision and eye-related quality of life (ER-QOL) in children and their families using the Pediatric Eye Questionnaire (PedEyeQ).
designProspective cross-sectional study.
methodsSeventeen children with residual amblyopia (no current treatment except glasses), 48 visually normal controls without glasses, and 19 controls wearing glasses (aged 8-11 years) completed the Child 5-11 year PedEyeQ. One parent for each child completed the Proxy 5-11 PedEyeQ, Parent PedEyeQ. Rasch-calibrated domain scores were calculated for each questionnaire domain and compared between amblyopic children and controls.
resultsPedEyeQ scores were significantly lower (worse) for children with residual amblyopia than for controls without glasses across all domains: Child PedEyeQ greatest mean difference 18 points worse on Functional vision domain (95% confidence interval [CI] -29 to -7; P < .001); Proxy PedEyeQ greatest mean difference 31 points worse on Functional vision domain (95% CI -39 to -24; P < .001); Parent PedEyeQ greatest mean difference 34 points worse on the Worry about child's eye condition domain (95% CI -46 to -22; P < .001). Compared with controls wearing glasses, PedEyeQ scores were lower for residual amblyopia on the Child Frustration/worry domain (P = .03), on 4 of 5 Proxy domains (P ≤ .05), and on 3 of 4 Parent domains (P ≤ .05).
conclusionsResidual amblyopia affects functional vision and ER-QOL in children. Parents of amblyopic children also experience lower quality of life. These data help broaden our understanding of the everyday-life impact of childhood residual amblyopia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.