Evidence map›Paper›PMID 32511848›Full record

ArticleJournal of veterinary internal medicine2020

A wireless endoscopy capsule suitable for imaging of the equine stomach and small intestine.

Mei Steinmann, Rebecca J Bezugley, Stephanie L Bond, Jill S Pomrantz, Renaud Léguillette

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Gastrointestinal biopsy in the horse: overview of collection, interpretation, and applications.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Mei SteinmannFaculty of Veterinary Medicine, Department of Veterinary Clinical and Diagnostic Services, University of Calgary, Calgary, Alberta, Canada.
Rebecca J BezugleyMoore Equine Veterinary Centre, Rocky View County, Alberta, Canada.
Stephanie L BondFaculty of Veterinary Medicine, Department of Veterinary Clinical and Diagnostic Services, University of Calgary, Calgary, Alberta, Canada.ORCID https://orcid.org/0000-0002-6700-5127
Jill S PomrantzInfiniti Medical, LLC, Menlo Park, California, USA.
Renaud LéguilletteFaculty of Veterinary Medicine, Department of Veterinary Clinical and Diagnostic Services, University of Calgary, Calgary, Alberta, Canada.ORCID https://orcid.org/0000-0003-0381-3640
University of Calgary · CAATUM (United States) · US

Funding

Department of Veterinary Clinical and Diagnostic Services, University of Calgary
6 · The paper itself

Abstract

backgroundCapsule endoscopy offers a new method for visualization of the gastrointestinal mucosa in horses where other imaging technologies have diagnostic limitations.

objectivesTo (1) test the feasibility of using this novel endoscopy capsule to visualize intestinal mucosa in horses, including an objective assessment of image quality, (2) assess how changes in preadministration preparation affect the transit time and the amount of gastrointestinal mucosa visualized, and (3) describe intestinal mucosa lesions in healthy horses. ANIMALS: Five healthy adult horses.

methodsThree protocols were used in a crossover study design. Protocols varied in time fasted, amount of oral fluid administered, and exercise. Manure was radiographically inspected for capsule recovery. Percentage of visible gastrointestinal mucosa was objectively assessed.

resultsDetailed images of the gastrointestinal mucosa were recorded with all 3 protocols, including images of the pylorus, major duodenal papilla, individual villi, and ileocecal junction. Visualization of large intestinal mucosa was poor. Interobserver agreement on image quality was excellent. Capsule administration after feed withholding for 24 hours provided the greatest percentage of visible mucosa in the stomach and small intestine. Total transit time to capsule excretion was 6.5 (3-8.75) days. Of 15 capsules administered, 3 were not recovered. Lesions visualized included mucosal erosion, ulceration and hemorrhage, areas of thickened mucosa, and evidence of parasitism.

conclusionsThis novel endoscopic capsule appears safe, practical, and noninvasive in horses; however, variability in capsule excretion time must be taken into account for clinical application.

Indexed as

AnimalsCapsule EndoscopyCross-Over StudiesFemaleGastrointestinal TransitHorse DiseasesHorsesIntestinal MucosaIntestine, SmallMaleStomachcapsule endoscopyendoscopygastroscopy

Identifiers

PMID32511848
PMCPMC7379013
OpenAlexW3034078069

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.