Evidence map›Paper›PMID 32511810›Full record

ArticleNeurourology and urodynamics2020

Best practices for cystometric evaluation of lower urinary tract function in muriform rodents.

Matthew O Fraser, Phillip P Smith, Maryrose P Sullivan, Dale E Bjorling, Lysanne Campeau, Karl-Erik Andersson, Mitsuharu Yoshiyama

Open access · greenAbstract read
In one paragraph

Article in Neurourology and urodynamics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
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  5. Review
  6. Spoti-find: a novel, open-source void spot assay image analysis tool.American journal of physiology. Renal physiology · 2026
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  9. Impact of surgical bladder catheter implantation on voiding function in mice.American journal of physiology. Regulatory, integrative and comparative physiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 4 countries.

Matthew O FraserDivision of Urology, Department of Surgery, Duke University Medical Center, Durham, North Carolina.ORCID 0000-0003-3022-0015
Phillip P SmithDivision of Urology, Department of Surgery, University of Connecticut Medical Center, Farmington, Connecticut.ORCID 0000-0003-0160-8387
Maryrose P SullivanDivision of Urology, Department of Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Dale E BjorlingDepartment of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin.
Lysanne CampeauDivision of Urology, Department of Surgery, McGill University, Montreal, Quebec, Canada.
Karl-Erik AnderssonInstitute for Regenerative Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina.ORCID 0000-0003-0665-3486
Mitsuharu YoshiyamaDepartment of Urology, University of Yamanashi Graduate School of Medicine, Chuo, Yamanashi, Japan.ORCID 0000-0001-8695-884X
Brigham and Women's Hospital · USDuke Medical Center · USLund University · SEMcGill University · CAUConn Health · USUniversity of Wisconsin–Madison · USUniversity of Yamanashi Hospital · JP

Funding

Role of Beta-Catenin in Urinary DysfunctionU54DK104310 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI RICKE, WILLIAM A · 2014 to 2023
$12.8M
Detrusor Underactivity as an HCN-mediated Failure of Resilience in AgingR01AG058814 · NIA · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI KUCHEL, GEORGE A, LEVINE, ERIC S · 2019 to 2023
$3.1M
Regulatory Mechanisms in a Homeostatic Model of Geriatric Voiding Problems and IncontinenceK76AG054777 · NIA · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI SMITH, PHILLIP PAUL · 2016 to 2018
$805k
Effect of Type II Diabetes on Bladder FunctionI01BX001790 · VA · VA BOSTON HEALTH CARE SYSTEM · PI MARYROSE P SULLIVAN · 2013 to 2026
–
Pelvic Visceral Interaction Following Spinal Cord InjuryI21RX001398 · VA · DURHAM VA MEDICAL CENTER · PI FRASER, MATTHEW O · 2015 to 2016
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Using aberrant pelvic reflexes to facilitate walking following spinal cord injuryI21RX001749 · VA · DURHAM VA MEDICAL CENTER · PI FRASER, MATTHEW O · 2015 to 2017
–
BLRD VA I01 BX001790NIA NIH HHS K76 AG054777NIA NIH HHS R01 AG058814NIDDK NIH HHS U54 DK104310RRD VA I21 RX001398RRD VA I21 RX001749
6 · The paper itself

Abstract

aimsRodent cystometry has provided valuable insights into the impact of the disease, injury, and aging on the cellular and molecular pathways, neurologic processes, and biomechanics of lower urinary tract function. The purpose of this white paper is to highlight the benefits and shortcomings of different experimental methods and strategies and to provide guidance on the proper interpretation of results.

methodsLiterature search, selection of articles, and conclusions based on discussions among a panel of workers in the field.

resultsA range of cystometric tests and techniques used to explore biological phenomena relevant to the lower urinary tract are described, the advantages and disadvantages of various experimental conditions are discussed, and guidance on the practical aspects of experimental execution and proper interpretation of results are provided.

conclusionsCystometric evaluation of rodents comprises an extensive collection of functional tests that can be performed under a variety of experimental conditions. Decisions regarding which approaches to choose should be determined by the specific questions to be addressed and implementation of the test should follow standardized procedures.

Indexed as

Urinary Tract Physiological PhenomenaAnimalsFemaleMaleRodentiaUrinary BladderUrodynamicspreclinical researchrodent cystometryurethraurinary bladderurodynamicswhite paper

Identifiers

PMID32511810
PMCPMC7641986
OpenAlexW3033497556

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.