Evidence map›Paper›PMID 32511577›Full record

ArticlemedRxiv : the preprint server for health sciences2020

Microwave-Generated Steam Decontamination of N95 Respirators Utilizing Universally Accessible Materials.

Katelyn E Zulauf, Alex B Green, Alex N Nguyen, Tanush Jagdish, Dvir Reif, Robert Seeley, Alana Dale, James E Kirby

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Katelyn E ZulaufDepartment of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Alex B GreenDepartment of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Alex N NguyenDepartment of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA, USA.
Tanush JagdishProgram for Systems, Synthetic, and Quantitative Biology, Harvard University, Cambridge, MA, USA.
Dvir ReifDepartment of Molecular and Cellular Biology, Harvard University, Cambridge, MA, USA.
Robert SeeleyEnvironmental Health and Safety Department, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Alana DaleEnvironmental Health and Safety Department, Beth Israel Deaconess Medical Center, Boston, MA, USA.
James E KirbyDepartment of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA.

Funding

INFECTIOUS DISEASE AND BASIC MICROBIOLOGICAL MECHANISMST32AI007061 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Marcia B Goldberg · 1985 to 2026
$12.1M
NIAID NIH HHS T32 AI007061
6 · The paper itself

Abstract

The SARS-CoV-2 pandemic has caused a severe, international shortage of N95 respirators, which are essential to protect healthcare providers from infection. Given the contemporary limitations of the supply chain, it is imperative to identify effective means of decontaminating, reusing, and thereby conserving N95 respirator stockpiles. To be effective, decontamination must result in sterilization of the N95 respirator without impairment of respirator filtration or user fit. Although numerous methods of N95 decontamination exist, none are universally accessible. In this work we describe a microwave-generated steam decontamination protocol for N95 respirators for use in healthcare systems of all sizes, geographies, and means. Using widely available glass containers, mesh from commercial produce bags, a rubber band, and a 1100W commercially available microwave, we constructed an effective, standardized, and reproducible means of decontaminating N95 respirators. Employing this methodology against MS2 phage, a highly conservative surrogate for SARS-CoV-2 contamination, we report an average 6-log

Identifiers

PMID32511577
PMCPMC7276004

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.