Evidence map›Paper›PMID 32511414›Full record

ArticlebioRxiv : the preprint server for biology2020

Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein.

Seth J Zost, Pavlo Gilchuk, Rita E Chen, James Brett Case, Joseph X Reidy, Andrew Trivette, Rachel S Nargi, Rachel E Sutton, Naveenchandra Suryadevara, Elaine C Chen and 18 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 60 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

28 authors at 7 institutions in 2 countries.

Seth J Zost
Pavlo Gilchuk
Rita E Chen
James Brett Case
Joseph X Reidy
Andrew Trivette
Rachel S Nargi
Rachel E Sutton
Naveenchandra Suryadevara
Elaine C Chen
Elad Binshtein
Swathi Shrihari
Mario Ostrowski
Helen Y Chu
Jonathan E Didier
Keith W MacRenaris
Taylor Jones
Samuel Day
Luke Myers
F Eun-Hyung Lee
Doan C Nguyen
Ignacio Sanz
David R Martinez
Ralph S Baric
Larissa B Thackray
Michael S Diamond
Robert H CarnahanORCID 0000-0001-5230-1532
James E Crowe
Vanderbilt University Medical Center · USWashington University in St. Louis · USEmory University · USLightSpin Technologies (United States) · USUniversity of North Carolina at Chapel Hill · USUniversity of Toronto · CAUniversity of Washington · US

Funding

Regulation of B cell Responses in SLE and Other Autoimmune DiseasesU19AI110483 · NIAID · EMORY UNIVERSITY · PI JEREMY M. BOSS · 2014 to 2026
$76.6M
NIAID NIH HHS U19 AI110483
6 · The paper itself

Abstract

Antibodies are a principal determinant of immunity for most RNA viruses and have promise to reduce infection or disease during major epidemics. The novel coronavirus SARS-CoV-2 has caused a global pandemic with millions of infections and hundreds of thousands of deaths to date

Identifiers

PMID32511414
PMCPMC7263562
OpenAlexW3025769737

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.