Evidence map›Paper›PMID 32511409›Full record

ArticlebioRxiv : the preprint server for biology2020

Potently neutralizing human antibodies that block SARS-CoV-2 receptor binding and protect animals.

Seth J Zost, Pavlo Gilchuk, James Brett Case, Elad Binshtein, Rita E Chen, Joseph X Reidy, Andrew Trivette, Rachel S Nargi, Rachel E Sutton, Naveenchandra Suryadevara and 21 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

31 authors at 5 institutions in 3 countries.

Seth J Zost
Pavlo Gilchuk
James Brett Case
Elad Binshtein
Rita E Chen
Joseph X Reidy
Andrew Trivette
Rachel S Nargi
Rachel E Sutton
Naveenchandra Suryadevara
Lauren E Williamson
Elaine C Chen
Taylor Jones
Samuel Day
Luke Myers
Ahmed O Hassan
Natasha M Kafai
Emma S Winkler
Julie M Fox
James J Steinhardt
Kuishu Ren
Yueh-Ming Loo
Nicole L Kallewaard
David R Martinez
Alexandra Schäfer
Lisa E Gralinski
Ralph S Baric
Larissa B Thackray
Michael S Diamond
Robert H CarnahanORCID 0000-0001-5230-1532
James E Crowe
Vanderbilt University Medical Center · USWashington University in St. Louis · USUniversity of North Carolina at Chapel Hill · USAstraZeneca (Australia) · AUAstraZeneca (United States) · US

Funding

Vanderbilt Biomedical Informatics Training ProgramT15LM007450 · NLM · VANDERBILT UNIVERSITY · PI Jessica S. Ancker, Bradley A. Malin · 2002 to 2026
$19.7M
NLM NIH HHS T15 LM007450
6 · The paper itself

Abstract

The COVID-19 pandemic is a major threat to global health for which there are only limited medical countermeasures, and we lack a thorough understanding of mechanisms of humoral immunity

Identifiers

PMID32511409
PMCPMC7263556
OpenAlexW3026583466

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.