Evidence map›Paper›PMID 32511384›Full record

ArticlebioRxiv : the preprint server for biology2020

Convergent Antibody Responses to SARS-CoV-2 Infection in Convalescent Individuals.

Davide F Robbiani, Christian Gaebler, Frauke Muecksch, Julio C C Lorenzi, Zijun Wang, Alice Cho, Marianna Agudelo, Christopher O Barnes, Anna Gazumyan, Shlomo Finkin and 36 more

Registry-linked trialOpen access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04573348 (Prospective, One Center, Four Groups, Open, Comparative, Controlled Study to Explore T Cells Response to SARS COV 2 Peptides by Metabolic Activity Method in Convalesce and Healthy Individuals Versus Antibody Response), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04573348 unknown statusnot on this map

Prospective, One Center, Four Groups, Open, Comparative, Controlled Study to Explore T Cells Response to SARS COV 2 Peptides by Metabolic Activity Method in Convalesce and Healthy Individuals Versus Antibody Response

TypeobservationalSponsorSavicell Diagnostics LtdRan2020 to 2021Enrolled400ConditionsCovid19, Corona Virus InfectionArmsSavicell's ImmunoBiopsy™
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 140 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

46 authors at 5 institutions in 1 country.

Davide F RobbianiLaboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Christian GaeblerLaboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Frauke MueckschLaboratory of Retrovirology, The Rockefeller University, New York, NY 10065, USA.
Julio C C LorenziLaboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Zijun WangLaboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Alice ChoLaboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Marianna AgudeloLaboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Christopher O BarnesDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Anna GazumyanLaboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Shlomo FinkinLaboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Thomas HagglofLaboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Thiago Y OliveiraLaboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Charlotte ViantLaboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Arlene HurleyHospital Program Direction, The Rockefeller University, New York, NY 10065, USA.
Hans-Heinrich HoffmannLaboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA.
Katrina G MillardLaboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Rhonda G KostHospital Clinical Research Office, The Rockefeller University, New York, NY 10065, USA.
Melissa CipollaLaboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Kristie GordonLaboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Filippo BianchiniLaboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Spencer T ChenLaboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Victor RamosLaboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Roshni PatelLaboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Juan DizonLaboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Irina ShimeliovichLaboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Pilar MendozaLaboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Harald HartwegerLaboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Lilian NogueiraLaboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Maggi PackLaboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Jill HorowitzLaboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Fabian SchmidtLaboratory of Retrovirology, The Rockefeller University, New York, NY 10065, USA.
Yiska WeisblumLaboratory of Retrovirology, The Rockefeller University, New York, NY 10065, USA.
Eleftherios MichailidisLaboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA.
Alison W AshbrookLaboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA.
Eric WaltariChan Zuckerberg Biohub, 499 Illinois Street, San Francisco, CA 94158, USA.
John E PakChan Zuckerberg Biohub, 499 Illinois Street, San Francisco, CA 94158, USA.
Kathryn E Huey-TubmanDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Nicholas KorandaDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Pauline R HoffmanDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Anthony P WestDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Charles M RiceLaboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA.
Theodora HatziioannouLaboratory of Retrovirology, The Rockefeller University, New York, NY 10065, USA.
Pamela J BjorkmanDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Paul D BieniaszLaboratory of Retrovirology, The Rockefeller University, New York, NY 10065, USA.
Marina CaskeyLaboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Michel C NussenzweigLaboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Rockefeller University · USCalifornia Institute of Technology · USChan Zuckerberg Initiative (United States) · USHoward Hughes Medical Institute · USRockefeller University Hospital · US

Funding

Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational SuccessUL1TR001866 · NCATS · ROCKEFELLER UNIVERSITY · PI COLLER, BARRY, KRUEGER, JAMES G · 2016 to 2025
$40.6M
Understanding B cell memory in response to diverse virus infectionsU19AI111825 · NIAID · ROCKEFELLER UNIVERSITY · PI RAVETCH, JEFFREY VICTOR · 2014 to 2023
$26.0M
Virus TransmissionP50AI150464 · NIAID · UNIVERSITY OF UTAH · PI HOPE, THOMAS · 2019 to 2021
$14.9M
Overcoming Host Restriction Factors to Develop Better Animal Models for HIV/AIDS.R01AI078788 · NIAID · ROCKEFELLER UNIVERSITY · PI HATZIIOANNOU, THEODORA · 2008 to 2021
$9.3M
Type I interferon-stimulated genes and the antiviral immune responseR01AI091707 · NIAID · ROCKEFELLER UNIVERSITY · PI RICE, CHARLES M · 2011 to 2020
$5.5M
Discovery and Mechanism of Antiretroviral FactorsR37AI064003 · NIAID · ROCKEFELLER UNIVERSITY · PI BIENIASZ, PAUL D. · 2011 to 2020
$4.9M
NCATS NIH HHS UL1 TR001866NIAID NIH HHS P50 AI150464NIAID NIH HHS R01 AI078788NIAID NIH HHS R01 AI091707NIAID NIH HHS R37 AI064003NIAID NIH HHS U19 AI111825
6 · The paper itself

Abstract

During the COVID-19 pandemic, SARS-CoV-2 infected millions of people and claimed hundreds of thousands of lives. Virus entry into cells depends on the receptor binding domain (RBD) of the SARS-CoV-2 spike protein (S). Although there is no vaccine, it is likely that antibodies will be essential for protection. However, little is known about the human antibody response to SARS-CoV-2

Identifiers

PMID32511384
PMCPMC7263513
OpenAlexW3024236348

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.