Evidence map›Paper›PMID 32511229›Full record

ArticlePLoS medicine2020

Population ageing and mortality during 1990-2017: A global decomposition analysis.

Xunjie Cheng, Yang Yang, David C Schwebel, Zuyun Liu, Li Li, Peixia Cheng, Peishan Ning, Guoqing Hu

Abstract read
In one paragraph

Article in PLoS medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 291 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
291citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

291 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  16. Observational
  17. Global, regional, and national burden of Clostridioides difficile infection (1990-2021) with projections to 2051: A multimodal analysis integrating machine learning (SHAP-XGBoost) and GBD 2021 data.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  18. Article
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  20. Article

231 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xunjie ChengDepartment of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha, China.
Yang YangDepartment of Biostatistics, College of Public Health and Health Professions, University of Florida, Gainesville, Florida, United States of America.
David C SchwebelDepartment of Psychology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.ORCID 0000-0002-2141-8970
Zuyun LiuDepartment of Pathology, Yale School of Medicine, New Haven, Connecticut, United States of America.ORCID 0000-0001-6120-5913
Li LiDivision of Epidemiology, College of Public Health, Ohio State University, Columbus, Ohio, United States of America.ORCID 0000-0002-6701-6993
Peixia ChengDepartment of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha, China.
Peishan NingDepartment of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha, China.ORCID 0000-0002-9919-4495
Guoqing HuDepartment of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha, China.ORCID 0000-0002-5002-8015

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAs the number of older people globally increases, health systems need to be reformed to meet the growing need for medical resources. A few previous studies reported varying health impacts of population ageing, but they focused only on limited countries and diseases. We comprehensively quantify the impact of population ageing on mortality for 195 countries/territories and 169 causes of death. METHODS AND

findingsUsing data from the Global Burden of Disease Study 2017 (GBD 2017), this study derived the total number of deaths and population size for each year from 1990 to 2017. A decomposition method was used to attribute changes in total deaths to population growth, population ageing, and mortality change between 1990 and each subsequent year from 1991 through 2017, for 195 countries/territories and for countries grouped by World Bank economic development level. For countries with increases in deaths related to population ageing, we calculated the ratio of deaths attributed to mortality change to those attributed to population ageing. The proportion of people aged 65 years and older increased globally from 6.1% to 8.8%, and the number of global deaths increased by 9 million, between 1990 and 2017. Compared to 1990, 12 million additional global deaths in 2017 were associated with population ageing, corresponding to 27.9% of total global deaths. Population ageing was associated with increases in deaths in high-, upper-middle-, and lower-middle-income countries but not in low-income countries. The proportions of deaths attributed to population ageing in 195 countries/territories ranged from -43.9% to 117.4% for males and -30.1% to 153.5% for females. The 2 largest contributions of population ageing to disease-specific deaths globally between 1990 and 2017 were for ischemic heart disease (3.2 million) and stroke (2.2 million). Population ageing was related to increases in deaths in 152 countries for males and 159 countries for females, and decreases in deaths in 43 countries for males and 36 countries for females, between 1990 and 2017. The decreases in deaths attributed to mortality change from 1990 to 2017 were more than the increases in deaths related to population ageing for the whole world, as well as in 55.3% (84/152) of countries for males and 47.8% (76/159) of countries for females where population ageing was associated with increased death burden. As the GBD 2017 does not provide variances in the estimated death numbers, we were not able to quantify uncertainty in our attribution estimates.

conclusionsIn this study, we found that population ageing was associated with substantial changes in numbers of deaths between 1990 and 2017, but the attributed proportion of deaths varied widely across country income levels, countries, and causes of death. Specific preventive and therapeutic techniques should be implemented in different countries and territories to address the growing health needs related to population ageing, especially targeting the diseases associated with the largest increase in number of deaths in the elderly.

Indexed as

AgingMortalityAdultAgedAge FactorsCause of DeathCost of IllnessFemaleGlobal HealthHealth Services Needs and DemandHumansMaleMiddle AgedModels, StatisticalPopulation DynamicsSex Factors

Identifiers

PMID32511229
PMCPMC7279585

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.