ArticlePLoS neglected tropical diseases2020
Assessing the burden and spatial distribution of Taenia solium human neurocysticercosis in Ecuador (2013-2017).
Article in PLoS neglected tropical diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 13 citations in OpenAlex.
- Neurocysticercosis in Ecuador: Spatial clustering, social determinants, and epidemiological trends (2017-2023).PLoS neglected tropical diseases · 2025Article
- Geostatistical analysis of active human cysticercosis: Results of a large-scale study in 60 villages in Burkina Faso.PLoS neglected tropical diseases · 2023Article
- A Spatial Autocorrelation Method forTropical medicine and infectious disease · 2023Article
- Improved latrine coverage may reduce porcine cysticercosis: a comparative cross-sectional study, Busia County, Kenya 2021.Frontiers in veterinary science · 2023Article
- Assessing the burden of Taenia solium cysticercosis in Burundi, 2020.BMC infectious diseases · 2022Article
- A scoping review of burden of disease studies estimating disability-adjusted life years due to Taenia solium.PLoS neglected tropical diseases · 2022Article
- Foodborne Parasitic Diseases in the Neotropics - A Review.Helminthologia · 2021Article
- Socio-economic and health costs of porcine/human cysticercosis, neurocysticercosis and epilepsy to small-scale pig producers in Tanzania.Bulletin of the National Research Centre · 2021Review
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6 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundEstimating the burden of neglected tropical diseases is a valuable tool to support policymakers in the resource allocation for control and elimination of these diseases. Spatial analysis allows to identify the geographical distribution patterns of infectious and parasitic diseases within a country and allows to assess their possible correlation with other health disorders. Despite being neurocysticercosis (NCC) considered as the most important parasitic disease of the nervous system, few efforts have been addressed to assess the real burden of NCC in endemic countries, to date, there are no studies estimating the burden of NCC in South America. In this study we aimed to use the Disability Adjust Life Years (DALY) and spatial indicators as tools to measure the impact of human neurocysticercosis in Ecuador between 2013 and 2017.
methodsMortality, morbidity and spatial data from the national agency of statistics were used to estimate the burden of disease of NCC during a five-year period (2013-2017). NCC cases and its two main sequelae, epilepsy and migraine headache, were stratified by sex and age group to calculate the DALY associated to NCC using the DALY package in R. SATSCAN software was used to assess spatial clusters of NCC and its possible neurological sequelae as epilepsy, status epilepticus, migraine and hydrocephalus. PRINCIPAL
findingsThe burden of human neurocysticercosis ranged from 56201 [95% CI 29961-89333] to 59612 [95% CI 31854-94689] DALY per year, corresponding to 3.54 to 3.56 DALY per 1000 population. Average yearly incidence rates per 10 000 person-years were 0.23 [95% CI 0.21-0.26] for NCC, 4.89 [95% CI 4.78-5.00] for epilepsy, 0.130 [95% CI 0.11-0.15] for status epilepticus, 0.62 [95% CI 0.58-0.66] for migraine headache, and 1.02 [95% CI 0.98-1.07] for hydrocephalus. Most important significant spatial clusters (p<0.0001) were located in the southern region of the highlands of the country. CONCLUSION/SIGNIFICANCE: This is the first study in South America to calculate estimates for burden of NCC and one of the few using spatial analysis to show the importance of sequelae other than epilepsy that play an important role in the impact of human neurocysticercosis.
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